01426nas a2200193   4500008004100000022001400041245007200055210006900127260011000196300001600306490000700322520068800329100001701017700002301034700002101057700002401078700002201102856010801124       2014                        eng d  a1359-734500aMulticomponent reactions involving phosphines, arynes and aldehydes0 aMulticomponent reactions involving phosphines arynes and aldehyd  aTHOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLANDbROYAL SOC CHEMISTRYcAUG  a11389-113920 v503 a<p>Although nucleophilic phosphine-catalysis is a powerful tool for the construction of various carbocycles and heterocycles, the reactions in which phosphines are incorporated into the final product are rare, and the reports on phosphine addition to highly electrophilic arynes are scarce. Herein, we report the phosphine triggered multicomponent reaction of arynes and aldehydes, which takes place via the formal [3+2] cycloaddition of an initially generated 1,3-phosphonium zwitterion from phosphines and arynes with aldehydes. The reaction resulted in the formation of a diverse range of stable pentacovalent phosphoranes in good yields based on the benzooxaphosphole system.</p>1 aBhunia, Anup1 aKaicharla, Trinadh1 aPorwal, Digvijay1 aGonnade, Rajesh, G.1 aBiju, Akkattu, T.  uhttps://library.ncl.res.in/content/multicomponent-reactions-involving-phosphines-arynes-and-aldehydes-0