01758nas a2200229   4500008004100000022001400041245016800055210006900223260010600292300001200398490000800410520078600418653004701204653001401251653002301265653001101288100002901299700002101328700002601349700002101375856013201396       2014                        eng d  a1386-142500aSynthesis, spectroscopic characterization and structural investigations of new adduct compound of carbazole with picric acid: DNA binding and antimicrobial studies0 aSynthesis spectroscopic characterization and structural investig  aTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLANDbPERGAMON-ELSEVIER SCIENCE LTDcJAN  a399-4060 v1183 a<p>Carbazole picrate (CP), a new organic compound has been synthesized, characterized by various analytical and spectroscopic technique such as FT-IR, UV-Vis, H-1 and C-13 NMR spectroscopy. An orthorhombic geometry was proposed based on single crystal XRD study. The thermal stability of the crystal was studied by using thermo-gravimetric and differential thermal analyses and found that it was stable up to 170 degrees C. Further, the newly synthesized title compound was tested for its in vitro antibacterial and antifungal activity against various bacterial and fungal species. Also, the compound was tested for its binding activity with Calf thymus (CT) DNA and the results show a considerable interaction between CP and CT-DNA. (C) 2013 Elsevier B.V. All rights reserved.</p>10aAntimicrobial activity and DNA-interaction10aCP adduct10aSingle crystal XRD10aTG-DTA1 aSaravanabhavan, Munusamy1 aSathya, Krishnan1 aPuranik, Vedavati, G.1 aSekar, Marimuthu  uhttps://library.ncl.res.in/content/synthesis-spectroscopic-characterization-and-structural-investigations-new-adduct-compound-0