01416nas a2200157   4500008004100000022001400041245021600055210006900271260007100340300001400411490000700425520065200432100002401084700001901108856013101127       2014                        eng d  a1523-706000aDiversity oriented convergent access for collective total synthesis of bioactive multifunctional carbazole alkaloids: synthesis of carbazomycin A, carbazomycin B, hyellazole, chlorohyellazole, and clausenaline D0 aDiversity oriented convergent access for collective total synthe  a1155 16TH ST, NW, WASHINGTON, DC 20036 USAbAMER CHEMICAL SOCcOCT  a5470-54730 v163 a<p>Facile syntheses of imperative carbazole alkaloids carbazomycin A, carbazomycin B, hyellazole, chlorohyellazole, and clausenaline D have been demonstrated starting from readily available Boc-protected 3-formylindole and dimethyl maleate. The suitably substituted aromatic rings have been designed comprising three/four significant C-C bond forming reactions. The competent Wittig reaction, selective monoalkylations, one-pot regioselective Weinreb amide formation and Boc-deprotection, well designed Grignard reactions, dehydrative intramolecular cyclizations, and Baeyer-Villiger rearrangement of aromatic aldehydes were the main features.</p>1 aMarkad, Shivaji, B.1 aArgade, N., P.  uhttps://library.ncl.res.in/content/diversity-oriented-convergent-access-collective-total-synthesis-bioactive-multifunctional-0