01417nas a2200181   4500008004100000022001400041245013900055210006900194260011000263300001600373490000600389520061400395100002301009700002001032700003701052700002301089856012301112       2015                        eng d  a2046-206900aRecyclable ionic liquid iodinating reagent for solvent free, regioselective iodination of activated aromatic and heteroaromatic amines0 aRecyclable ionic liquid iodinating reagent for solvent free regi  aTHOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLANDbROYAL SOC CHEMISTRYcOCT  a88311-883150 v53 a<p>This article describes a simple, efficient method for iodination of activated aromatic and heteroaromatic amines using recyclable 1-butyl-3-methylpyridinium dichloroiodate (BMPDCI) as an ionic liquid iodinating reagent, in the absence of any solvent. The main advantages are a simple efficient procedure, good yields and no need for any base/toxic heavy metals, or oxidizing agents. The ionic liquid was recovered and recycled in five subsequent reactions, without much loss of activity. This method was applied for the synthesis of the antiprotozoal drug iodoquinol and the antifungal drug clioquinol.</p>1 aDeshmukh, Amarsinh1 aGore, Babasaheb1 aThulasiram, Hirekodathakallu, V.1 aSwamy, Vincent, P.  uhttps://library.ncl.res.in/content/recyclable-ionic-liquid-iodinating-reagent-solvent-free-regioselective-iodination-0