01477nas a2200205   4500008004100000022001400041245011000055210006900165260011000234300001600344490000700360520061100367100003200978700002701010700003401037700001501071700003701086700002501123856012301148       2015                        eng d  a1359-734500aAssessing the effect of different shapes of glyco-gold nanoparticles on bacterial adhesion and infections0 aAssessing the effect of different shapes of glycogold nanopartic  aTHOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLANDbROYAL SOC CHEMISTRYcAUG  a15669-156720 v513 a<p>Achieving selective and sensitive carbohydrate-protein interactions (CPIs) using nanotechnology is an intriguing area of research. Here we demonstrate that the different shapes of gold nanoparticles (AuNPs) functionalized with monosaccharides tune the bacterial aggregations. The mechanism of aggregation revealed that the large number of surface interactions of rod shaped mannose-AuNPs with E. coli ORN 178 compared with spherical and star-shaped AuNPs exhibited higher avidity and sensitivity. Moreover, such sensitive binding can be used for effective inhibition of bacterial infection of cells.</p>1 aChaudhary, Preeti, Madhukar1 aSangabathuni, Sivakoti1 aMurthy, Raghavendra, Vasudeva1 aPaul, Ajay1 aThulasiram, Hirekodathakallu, V.1 aKikkeri, Raghavendra  uhttps://library.ncl.res.in/content/assessing-effect-different-shapes-glyco-gold-nanoparticles-bacterial-adhesion-and-0