01175nas a2200181   4500008004100000022001400041245011300055210006900168260011000237300001400347490000700361520040400368100002600772700002900798700002000827700002200847856012400869       2016                        eng d  a1359-734500aFrom insertion to multicomponent coupling: temperature dependent reactions of arynes with aliphatic alcohols0 aFrom insertion to multicomponent coupling temperature dependent   aTHOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLANDbROYAL SOC CHEMISTRYcNOV  a1665-16680 v523 a<p>The temperature dependent selectivity switch in the reaction of arynes with aliphatic alcohols in THF has been reported. At -20 degrees C, arynes smoothly insert into the O-H bond of alcohols to form alkyl aryl ethers. Interestingly, at 60 degrees C, a highly selective multicomponent coupling occurs with the solvent THF acting as the nucleophilic trigger affording (4-(alkoxy)butoxy)arenes.</p>1 aThangaraj, Manikandan1 aBhojgude, Sachin, Suresh1 aMane, Manoj, V.1 aBiju, Akkattu, T.  uhttps://library.ncl.res.in/content/insertion-multicomponent-coupling-temperature-dependent-reactions-arynes-aliphatic-0