01363nas a2200169   4500008004100000022001400041245016900055210006900224260007100293300001200364490000700376520060900383100002400992700002301016700002201039856013201061       2016                        eng d  a1523-706000aRegioselective oxo-amination of alkenes and enol ethers with N-bromosuccinimide-dimethyl sulfoxide combination: a facile synthesis of alpha-amino-ketones and esters0 aRegioselective oxoamination of alkenes and enol ethers with Nbro  a1155 16TH ST, NW, WASHINGTON, DC 20036 USAbAMER CHEMICAL SOCcFEB  a500-5030 v183 a<p>An unprecedented conversion of alkenes and enol ethers to the corresponding a-imido carbonyl compounds with excellent regioselectivity and yields has been developed. This oxo-amination process employs readily available N-bromosuccinimide (NBS) and secondary amines as N-sources and dimethyl sulfoxide (DMSO) as the oxidant and also leads to the production of amino alcohols in a single step on reduction, thus broadening the scope of this operationally simple reaction. For the first time, the formation of reactive Me2S+-O-Br species generated by the interaction of NBS with DMSO has been proven.</p>1 aPrasad, Pragati, K.1 aReddi, Rambabu, N.1 aSudalai, Arumugam  uhttps://library.ncl.res.in/content/regioselective-oxo-amination-alkenes-and-enol-ethers-n-bromosuccinimide-dimethyl-sulfoxide-0