01215nas a2200157   4500008004100000022001400041245011600055210006900171260007200240300001200312490000700324520056600331100001700897700002400914856011900938       2016                        eng d  a1367-480300aNo promoter left behind (NPLB): learn de novo promoter architectures from genome-wide transcription start sites0 aNo promoter left behind NPLB learn de novo promoter architecture  aGREAT CLARENDON ST, OXFORD OX2 6DP, ENGLANDbOXFORD UNIV PRESScMAR  a779-7810 v323 a<p>Promoters have diverse regulatory architectures and thus activate genes differently. For example, some have a TATA-box, many others do not. Even the ones with it can differ in its position relative to the transcription start site (TSS). No Promoter Left Behind (NPLB) is an efficient, organism-independent method for characterizing such diverse architectures directly from experimentally identified genome-wide TSSs, without relying on known promoter elements. As a test case, we show its application in identifying novel architectures in the fly genome.</p>1 aMitra, Sneha1 aNarlikar, Leelavati  uhttps://library.ncl.res.in/content/no-promoter-left-behind-nplb-learn-de-novo-promoter-architectures-genome-wide-0