@article {45947,
	title = {Chirality induction and chiron approaches to enantioselective total synthesis of alpha-lipoic acid},
	journal = {Tetrahedron},
	volume = {71},
	year = {2015},
	month = {JUN },
	pages = {4213-4218},
	type = {Article},
	abstract = {<p>An efficient, short and convenient asymmetric synthesis of (R)-(+)-lipoic acid in seven steps from chiral hydroxy aldehyde with 32.5\% overall yield is described. Synthesis of S and R enantiomers of a-lipoic acid from cis-1,4-butene diol derived chiral lactone is reported with 34 \% overall yield. The present synthesis involves use of simple reaction conditions making it a convenient synthesis. (C) 2015 Elsevier Ltd. All rights reserved.</p>},
	keywords = {Chiral pool, Chirality induction, enantioselective, Lipoic acid, sharpless asymmetric dihydroxylation},
	issn = {0040-4020},
	doi = {10.1016/j.tet.2015.04.090},
	author = {Chavan, Subhash P. and Pawar, Kailash P. and Praveen, Ch and Patil, Niteen B.}
}
@article {44502,
	title = {Synthesis of key intermediate for (+)-tofacitinib through CoIII(salen)-catalyzed two stereocentered hydrolytic kinetic resolution of ({\^A}{\textpm})-methyl-3-(oxiran-2-yl)butanoate},
	journal = { Synthetic Communications},
	volume = {48},
	year = {2018},
	month = {MAR},
	pages = {1045-1051},
	type = {Journal Article},
	abstract = {An enantiopure piperidine, a key intermediate for the synthesis of (+)-tofacitinib, has been achieved in high optical purity (98\% ee) from readily available crotyl alcohol. The key steps involved is a CoIII(salen)-OAc-catalyzed two stereocentered hydrolytic kinetic resolution of ({\textpm})-methyl-3-(oxiran-2-yl)butanoate.},
	keywords = {enantioselective, Hydrolytic kinetic resolution, iodolactonization, γ-Butyralactone},
	issn = {397911},
	doi = {10.1080/00397911.2018.1434204},
	author = {Kamble, Rohit B.},
	editor = {Suryavanshi, Gurunath}
}
