@article { ISI:000342568800011,
	title = {Synthesis of (+)-harmicine},
	journal = {Synthesis-Stuttgart},
	volume = {46},
	number = {19},
	year = {2014},
	month = {OCT},
	pages = {2591-2594},
	publisher = {GEORG THIEME VERLAG KG},
	address = {RUDIGERSTR 14, D-70469 STUTTGART, GERMANY},
	abstract = {<p>A facile convergent access to the important indole alkaloid (+)-harmicine is described, starting from tryptamine and (R)-acetoxysuccinic anhydride via the corresponding acetoxysuccinimide in very good overall yield. Regioselective reduction of an unsymmetrical imide carbonyl group and acid-catalyzed stereoselective intramolecular cyclization were the key features involved. The directing group to induce asymmetry was finally detached via the corresponding iodide by using tributyltin hydride chemistry.</p>},
	keywords = {alkaloids, cyclization, imides, reduction, stereoselective synthesis},
	issn = {0039-7881},
	doi = {10.1055/s-0034-1378381},
	author = {Mondal, Pravat and N. P. Argade}
}
@article { ISI:000356324000001,
	title = {Radical-mediated dehydrative preparation of cyclic imides using (NH4)(2)S2O8-DMSO: application to the synthesis of vernakalant},
	journal = {Beilstein Journal of Organic Chemistry},
	volume = {11},
	year = {2015},
	month = {JUN},
	pages = {1008-1016},
	publisher = {BEILSTEIN-INSTITUT},
	address = {TRAKEHNER STRASSE 7-9, FRANKFURT AM MAIN, 60487, GERMANY},
	abstract = {<p>Ammonium persulfate-dimethyl sulfoxide (APS-DMSO) has been developed as an efficient and new dehydrating reagent for a convenient one-pot process for the synthesis of miscellaneous cyclic imides in high yields starting from readily available primary amines and cyclic anhydrides. A plausible radical mechanism involving DMSO has been proposed. The application of this facile one-pot imide forming process has been demonstrated for a practical synthesis of vernakalant.</p>},
	keywords = {APS-DMSO, imides, practical synthesis, radical-mediated, vernakalant},
	issn = {1860-5397},
	doi = {10.3762/bjoc.11.113},
	author = {Garad, Dnyaneshwar N. and Tanpure, Subhash D. and Mhaske, Santosh B.}
}
