@article { ISI:000237937900022,
	title = {Enantioselective synthesis of (-)-cytoxazone and (+)-epi-cytoxazone, novel cytokine modulators via sharpless asymmetric epoxidation and L-proline catalyzed mannich reaction},
	journal = {Tetrahedron},
	volume = {62},
	number = {24},
	year = {2006},
	month = {JUN},
	pages = {5756-5762},
	publisher = {PERGAMON-ELSEVIER SCIENCE LTD},
	type = {Article},
	address = {THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND},
	abstract = {<p>A short and efficient enantioselective synthesis of (-)-cytoxazone and its stereoisomer (+)-epi-cytoxazone, novel cytokine modulators, has been described with good yield and enantioselectivity. Ti-catalyzed Sharpless asymmetric epoxidation of allyl alcohol and L-proline catalyzed three-component Mannich reaction constitute the key steps in introducing stereogenicity into the molecule. (c) 2006 Elsevier Ltd. All rights reserved.</p>},
	keywords = {aminohydroxylation, Asymmetric synthesis, epoxidation, Mannich reaction, Oxidation, Ozonolysis},
	issn = {0040-4020},
	doi = {10.1016/j.tet.2006.03.079},
	author = {Paraskar, Abhimanyu S. and Sudalai, Arumugam}
}
@article {47427,
	title = {Short enantioselective total synthesis of (+)-tofacitinib},
	journal = {Tetrahedron Letters},
	volume = {67},
	year = {2021},
	month = {MAR},
	pages = {152838},
	type = {Article},
	abstract = {<p>An enantioselective total synthesis of Tofacitinib (CP-690,550), a Janus tyrosine kinase (JAK3) specific inhibitor has been achieved from the readily available 4-piperidone. Proline catalysed hydroxylation is the key step for the synthesis of enantiopure 1-benzyl-4-methylpiperidin-3-ol. (C) 2021 Elsevier Ltd. All rights reserved.</p>},
	keywords = {aminohydroxylation, Hydrogenation, L-proline, piperidone},
	issn = {0040-4039},
	doi = {10.1016/j.tetlet.2021.152838},
	author = {Mane, Kishor D. and Kamble, Rohit B. and Suryavanshi, Gurunath}
}
