@article { ISI:000256004800004,
	title = {Studies on the synthesis and unusual behavior of vinyl sulfone-modified hexenopyranosylthymines},
	journal = {Carbohydrate Research},
	volume = {343},
	number = {7},
	year = {2008},
	month = {MAY},
	pages = {1163-1170},
	publisher = {ELSEVIER SCI LTD},
	address = {THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND},
	abstract = {<p>Although vinyl sulfone-modified- (VSM) pent-2-enofuranosyl nucleosides 2 and hex-2-enopyranosyl glycoside 4 are easily synthesized from the corresponding mesylated sulfones le and 3c, respectively, via an oxidation-mesylation-elimination route, the 3{\textquoteright}-C-sulfonyl-hex-2{\textquoteright}-enopyranosylthymine 11 is not obtained from 10 and a glycal derivative 12 is formed instead. On the other hand, 3-C-sulfonyl-hex-3{\textquoteright}-enopyranosylthymine 20 is easily synthesized from the mesylated sulfone 19. Again unlike the reaction patterns of VSM-pent-T-enofuranosyl nucleosides 2 and hex-2-enopyranosyl glycosides 4 as Michael acceptors, the reactions of nucleophiles with 3{\textquoteright}-C-sulfonyl-hex-3{\textquoteright}-enopyranosylthymine 20 yielded a rearranged product 21 instead of Michael adducts. (c) 2008 Published by Elsevier Ltd.</p>},
	keywords = {glycal, hexopyranosyl nucleosides, Michael addition, unsaturated nucleosides, vinyl sulfone-modified nucleosides},
	issn = {0008-6215},
	doi = {10.1016/j.carres.2008.02.016},
	author = {Deshpande, Sachin G. and Suresh, Cheravakkattu G. and Pathak, Tanmaya}
}
