@article { ISI:000246431300013, title = {Efficient one-pot synthesis of alpha-amino phosphonates catalyzed by bismuth nitrate pentahydrate}, journal = {Synlett}, number = {5}, year = {2007}, month = {MAR}, pages = {745-748}, publisher = {GEORG THIEME VERLAG KG}, type = {Article}, address = {RUDIGERSTR 14, D-70469 STUTTGART, GERMANY}, abstract = {

A simple, efficient, and environmentally benign method has been developed for the synthesis of alpha-amino phosphonates through a one-pot reaction of aldehydes with amines and diethyl phosphite in the presence of bismuth nitrate pentahydrate as a catalyst. Some of the major advantages of this protocol are: good yields, the involvement of a less-expensive and non-toxic catalyst, mild and solvent-free reaction conditions and also tolerance towards other functional groups present in the substrates. Eighteen examples are described, highlighting the substrate scope of the reaction.

}, keywords = {aldehydes, alkyl phosphite, alpha-amino phosphonates, amines, bismuth nitrate pentahydrate, synthetic methods}, issn = {0936-5214}, doi = {10.1055/s-2007-970762}, author = {Bhattacharya, Asish K. and Kaur, Tanpreet} } @article { ISI:000255318800025, title = {Amberlite-IR 120 catalyzed three-component synthesis of alpha-amino phosphonates in one-pot}, journal = {Tetrahedron Letters}, volume = {49}, number = {16}, year = {2008}, month = {APR}, pages = {2598-2601}, publisher = {PERGAMON-ELSEVIER SCIENCE LTD}, type = {Article}, address = {THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND}, abstract = {

A simple, efficient, and environmentally benign method for a three-component reaction of an amine, an aldehyde or a ketone, and diethyl phosphite catalyzed by Amberlite-IR 120 resin has been developed to afford alpha-amino phosphonates in high yields and short reaction times under solvent-free reaction conditions. The major advantages of the present method are good yields, inexpensive, ecofriendly and reusable catalyst, mild and solvent-free reaction conditions and tolerance towards various functionalities present in the substrates. (c) 2008 Elsevier Ltd. All rights reserved.

}, keywords = {aldehydes, alkyl phosphite, alpha-amino phosphonates, amines, ion-exchange resin, multi-component reaction}, issn = {0040-4039}, doi = {10.1016/j.tetlet.2008.02.102}, author = {Bhattacharya, Asish K. and Rana, Kalpeshkumar C.} } @article { ISI:000259412500023, title = {Synthesis of alpha-amino phosphonates by three component condensation of carbonyl compound, amine, and dialkyl phosphite using Yttria-zirconia based Lewis acid catalyst}, journal = {Catalysis Letters}, volume = {125}, number = {3-4}, year = {2008}, month = {OCT}, pages = {315-319}, publisher = {SPRINGER}, type = {Article}, address = {233 SPRING ST, NEW YORK, NY 10013 USA}, abstract = {

An efficient Yttria-zirconia Lewis acid catalyzed one-pot synthesis of alpha-amino phosphonates by three component coupling reaction of a carbonyl compound amine and dialkyl phosphates is described in good to high yield.

}, keywords = {alpha-amino phosphonates, three component coupling, Yttria-zirconia based Lewis acid catalyst}, issn = {1011-372X}, doi = {10.1007/s10562-008-9562-x}, author = {Ramalingam, S. and Kumar, Pradeep} }