@article { ISI:000286474600008,
	title = {(-)-6 alpha-Hydroxy polyanthellin A - a novel antifouling diterpenoid from the Indian soft coral Cladiella krempfi (Hickson)},
	journal = {Canadian Journal of Chemistry-Revue Canadienne De Chimie},
	volume = {89},
	number = {1},
	year = {2011},
	month = {JAN},
	pages = {57-60},
	publisher = {CANADIAN SCIENCE PUBLISHING, NRC RESEARCH PRESS},
	address = {1200 MONTREAL ROAD, BUILDING M-55, OTTAWA, ON K1A 0R6, CANADA},
	abstract = {<p>Bioassay-guided purification of methanol extract of the soft coral Cladiella krempfi (Octocorallia: Alcynocea) yielded a novel eunicellin-type diterpenoid, (-)-6 alpha-hydroxy polyanthellin A (1), active against the cyprids of the fouling barnacle, Balanus amphitrite (EC(50) 9.02 mu g/mL; LC(50) 36 mu g/mL; and therapeutic ratio = 4). The structure of compound 1 was determined from its spectral data, including IR, NMR (1D and 2D NMR), and mass spectra.</p>},
	keywords = {antifouling, Balanus amphitrite, biofouling, Cladiella krempfi, diterpenes},
	issn = {0008-4042},
	doi = {10.1139/V10-159},
	author = {Mol, V. P. Limna and Raveendran, T. V. and Parameswaran, P. S. and Kunnath, R. J. and Rajamohanan, P. R.}
}
@article { ISI:000368583100006,
	title = {New pimarane diterpenes and other antimycobacterial metabolites from anisochilus verticillatus},
	journal = {Natural Product Research},
	volume = {30},
	number = {6},
	year = {2016},
	month = {MAR},
	pages = {675-681},
	publisher = {TAYLOR \& FRANCIS LTD},
	address = {4 PARK SQUARE, MILTON PARK, ABINGDON OX14 4RN, OXON, ENGLAND},
	abstract = {<p>Phytochemical investigation of the acetone extract of the aerial parts of Anisochilus verticillatus afforded a new 8,9-secopimarane diterpene (1), two new isopimarane diterpenes (2, 3) and the known ursolic acid (4), beta-amyrin (5), -amyrin (6), stigmast-5-en-3-one (7) and hydroxychavicol (8). Structures of the new compounds were elucidated with the help of 1D and 2D nuclear magnetic resonance spectroscopic data, and single crystal X-ray crystallography of compound 3. Compounds 2 and 8 inhibited Mycobacterium tuberculosis H37Ra with an IC50 of 11.3 (IC90 of 20.0g/mL) and 12.5g/mL, respectively. Correspondingly, molecular docking studies with Extra Precision Glide revealed a correlation between score and biological activity for these compounds to describe the molecular basis for the most significant SAR results.</p>},
	keywords = {alanine racemase, Anisochilus verticillatus, antimycobacterial activity, diterpenes, Lamiaceae},
	issn = {1478-6419},
	doi = {10.1080/14786419.2015.1040990},
	author = {Kulkarni, Roshan R. and Shurpali, Ketaki and Khedkar, Vijay M. and Puranik, Vedavati G. and Sarkar, Dhiman and Joshi, Swati P.}
}
