@article { ISI:000234174800006, title = {Enantioselective synthesis of 1-azaspiro[5.5]undecane ring system of histrionicotoxin alkaloids from D(+)-glucose}, journal = {Heterocycles}, volume = {65}, number = {12}, year = {2005}, month = {DEC}, pages = {2901-2916}, publisher = {PERGAMON-ELSEVIER SCIENCE LTD}, type = {Article}, address = {THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND}, abstract = {

Histrionicotoxins, the archetype of a group of spiropiperidine containing alkaloids from the brightly colored poison arrow frog Dendrobates histronicus native to the Amazon rain forests of Southern Columbia, was first isolated by Daly, Witkop and co-workers in 1971.1 They all share a common Iazaspiro[5.5]undecan-8-ol ring system with unsaturated C4 or C5 side chains at both the 2 and 7 positions. The nature and length of the side chains distinguish the different members of the histrionicotoxin family.

}, keywords = {chiron approach, domino reaction, Ring closing metathesis}, issn = {0385-5414}, author = {Bera, Smritilekha} } @article { ISI:000231661800039, title = {Enantioselective synthesis of tarchonanthuslactone via iterative hydrolytic kinetic resolution}, journal = {Tetrahedron Letters}, volume = {46}, number = {38}, year = {2005}, month = {SEP}, pages = {6571-6573}, publisher = {PERGAMON-ELSEVIER SCIENCE LTD}, type = {Article}, address = {THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND}, abstract = {

A short and practical enantioselective synthesis of tarchonanthuslactone has been achieved in high diastereomeric excess using iterative Jacobsen{\textquoteright}s hydrolytic kinetic resolution and ring closing metathesis as the key steps. (c) 2005 Elsevier Ltd. All rights reserved.

}, keywords = {Jacobsen{\textquoteright}s hydrolytic kinetic resolution, Ring closing metathesis, tarchonanthuslactone}, issn = {0040-4039}, doi = {10.1016/j.tetlet.2005.07.056}, author = {Gupta, P and Naidu, SV and Kumar, P} } @article { ISI:000227411400025, title = {Synthetic studies toward tricyclic cembranoids: a modular approach for the construction of the tricyclic framework of eunicin}, journal = {Tetrahedron Letters}, volume = {46}, number = {11}, year = {2005}, month = {MAR}, pages = {1881-1884}, publisher = {PERGAMON-ELSEVIER SCIENCE LTD}, type = {Article}, address = {THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND}, abstract = {

The synthesis of a sugar derived allene and its intramolecular silver mediated etherification followed by ring closing metathesis has been explored for building the tricyclic framework of eunicin. (C) 2005 Elsevier Ltd. All rights reserved.

}, keywords = {Allene, Carbohydrate, cembranoid, eunicin, Ring closing metathesis}, issn = {0040-4039}, doi = {10.1016/j.tetlet.2005.01.094}, author = {Gurjar, MK and Nayak, S and Ramana, CV} } @article { ISI:000238012800020, title = {Synthetic studies toward macrocidins: an RCM approach for the construction of the central cyclic core}, journal = {Tetrahedron Letters}, volume = {47}, number = {24}, year = {2006}, month = {JUN}, pages = {4061-4064}, publisher = {PERGAMON-ELSEVIER SCIENCE LTD}, type = {Article}, address = {THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND}, abstract = {

The central macrocyclic core of the macrocidins was constructed using RCM as the key reaction. A preliminary investigation dealing with the key reactions, that is, the Dieckmann cyclization and the RCM, revealed that RCM of the beta-ketoamide is better than RCM of the corresponding acyltetramic acid. (c) 2006 Elsevier Ltd. All rights reserved.

}, keywords = {acyltetramic acid, Lacey-Dieckmann cyclization, macrocidins, Ring closing metathesis}, issn = {0040-4039}, doi = {10.1016/j.tetlet.2006.03.192}, author = {Ramana, C. V. and Mondal, Mohabul A. and Puranik, Vedavati G. and Gurjar, Mukund K.} } @article { ISI:000243819800025, title = {Central core of uprolides D and E: a survey of some ring closing metathesis approaches}, journal = {Tetrahedron Letter}, volume = {48}, number = {6}, year = {2007}, month = {FEB}, pages = {1013-1016}, publisher = {PERGAMON-ELSEVIER SCIENCE LTD}, type = {Article}, address = {THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND}, abstract = {

A preliminary study dealing with the feasibility of ring closing metathesis and ene-yne ring closing metathesis to construct the central bicyclic cores of uprolides D and E was investigated. (c) 2006 Elsevier Ltd. All rights reserved.

}, keywords = {cembranolides, ene-yne metathesis, Ring closing metathesis, Sharpless asymmetric epoxidation, uprolides D and E}, issn = {0040-4039}, doi = {10.1016/j.tetlet.2006.11.176}, author = {Ramana, C. V. and Salian, Sumanth R. and Gurjar, Mukund K.} } @article { ISI:000303429600017, title = {Formal synthesis of (-)-stemoamide using a useful epimerization at C-8}, journal = {Tetrahedron Letters}, volume = {53}, number = {21}, year = {2012}, month = {MAY}, pages = {2647-2650}, publisher = {PERGAMON-ELSEVIER SCIENCE LTD}, address = {THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND}, abstract = {

The formal synthesis of (-)-stemoamide was achieved starting from L-pyroglutamic acid. The key steps used are the allylation using BF3 center dot OEt2, ring closing metathesis, allylic oxidation and a novel epimerization at C8. (C) 2012 Elsevier Ltd. All rights reserved.

}, keywords = {Allylation, Allylic oxidation, Pyroglutamic acid, Ring closing metathesis, Stemoamide}, issn = {0040-4039}, doi = {10.1016/j.tetlet.2012.03.054}, author = {Chavan, Subhash P. and Harale, Kishor R. and Puranik, Vedavati G. and Gawade, Rupesh L.} } @article { ISI:000344204600027, title = {Total synthesis of mangiferaelactone}, journal = {Tetrahedron Letters}, volume = {55}, number = {45}, year = {2014}, month = {NOV}, pages = {6263-6265}, publisher = {PERGAMON-ELSEVIER SCIENCE LTD}, address = {THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND}, abstract = {

Herein we document the first total synthesis of mangiferaelactone and thus establish its absolute configuration. The central nonenolide ring was constructed using ring closing metathesis and Yamaguchi esterification. The key alcohol fragment was synthesized by the Bernet-Vasella fragmentation of C-ribofuranoside. (C) 2014 Elsevier Ltd. All rights reserved.

}, keywords = {Bernet-Vasella fragmentation, Nonenolide, Ring closing metathesis, Total synthesis, Yamaguchi protocol}, issn = {0040-4039}, doi = {10.1016/j.tetlet.2014.09.084}, author = {Vadhadiya, Paresh M. and Ramana, C. V.} } @article { ISI:000364885800006, title = {Studies toward the total synthesis of cytospolide E}, journal = {Tetrahedron}, volume = {71}, number = {48}, year = {2015}, month = {DEC}, pages = {9088-9094}, publisher = {PERGAMON-ELSEVIER SCIENCE LTD}, address = {THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND}, abstract = {

In this manuscript, we describe various approaches that we have examined towards the total synthesis of Cytospolide E. We initially attempted the RCM approach employing first and second generation Grubbs and Grubbs-Hoyeda catalysts resulting in the exclusive synthesis of the Z-isomer of Cytospolide E. With the Furstner catalyst, the dimerization involving the less hindered olefin was the exclusive event. Alternative approach documented is a successful cross-metathesis leading to a seco-acid with the requisite E-configuration and undesired macrodiolide formation during the attempted Shiina{\textquoteright}s lactonization. (C) 2015 Elsevier Ltd. All rights reserved.

}, keywords = {20-Membered macrodiolide, Nonenolide, Ring closing metathesis, Shiina lactonization, Yamaguchi esterification}, issn = {0040-4020}, doi = {10.1016/j.tet.2015.10.018}, author = {Vadhadiya, Paresh M. and Rout, Jeetendra K. and Ramana, C. V.} } @article {46941, title = {Concise enantioselective synthesis of (R)-(+)-goniothalamin oxide, a trypanocidal active agent via L-prolinol catalyzed asymmetric epoxidation of cinnamaldehyde}, journal = {Indian Journal of Chemistry Section B-Organic Chemistry Including Medicinal Chemistry}, volume = {59}, year = {2020}, month = {MAR}, pages = {393-398}, type = {Article}, abstract = {

A short and straight-forward enantioselective synthesis of (R)-(+)-goniothalamin oxide 2 has been achieved with an overall yield of 39\% and 99\% ee. The synthetic approach involves L-prolinol catalyzed asymmetric epoxidation of cinnamaldehyde followed by Lewis acid-mediated diastereoselective allylation of epoxy aldehyde as the key chiral-inducing steps.

}, keywords = {Allylation, asymmetric epoxidation, Esterification, Grubbs{\textquoteright} catalyst, L-prolinol catalyst, Ring closing metathesis}, issn = {0376-4699}, author = {Kumar, B. Senthil and Mandle, Ram D. and Kamble, Sanjay P. and Sudalai, Arumugam} }