@article { ISI:000339128700053,
	title = {Highly regioselective C4-hydrazinylation of 2,4-dichloroquinolines: expedient synthesis of aminoquinoline substituted pyrrolidin-2,5-diones via hydrazinylquinolines},
	journal = {Tetrahedron Letters},
	volume = {55},
	number = {30},
	year = {2014},
	month = {JUL},
	pages = {4240-4244},
	publisher = {PERGAMON-ELSEVIER SCIENCE LTD},
	address = {THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND},
	abstract = {<p>A new class of hydrazinylquinoline regio-isomers has been synthesized through SNAr reaction of 2,4-dichloroquinolines with hydrazine hydrate. The reaction stops at the mono-substitution product with high regioselectivity at the C-4 rather than C-2 position of dichloroquinolines. The hydrazinylquinolines were subsequently converted into aminoquinoline substituted pyrrolidin-2,5-diones in the presence of Eaton{\textquoteright}s reagent. (C) 2014 Elsevier Ltd. All rights reserved.</p>},
	keywords = {5-diones, Eaton{\textquoteright}s reagent, Hydrazinylquinolines, Pyrrolidin-2, Regioisomers, SNAr reaction},
	issn = {0040-4039},
	doi = {10.1016/j.tetlet.2014.05.132},
	author = {Kumar, Gopal Senthil and Zeller, Matthias and Gonnade, Rajesh Ghanshyam and Prasad, Kamam Jayarampillai Rajendra}
}
@article {47399,
	title = {gamma-Al2O3/triflic acid as cooperative catalysts for the tandem Michael addition/carbocyclization: an easy access to 2-substituted pyrrolo[2,1-a]isoquinolines and 3-substituted pyrrolidine-2,5-diones},
	journal = {Journal of Heterocyclic Chemistry},
	volume = {58},
	year = {2021},
	month = {JUL},
	pages = {1415-1428},
	type = {Article},
	abstract = {<p>A tandem Michael addition/carbocyclization of 3,4-dimethoxyphenethyl maleimide with carbon and sulfur nucleophiles is accomplished via a relay catalysis using gamma-Al2O3/TfOH binary system. The X-ray Photoelectron Spectroscopy (XPS) analysis of binary system indicates the presence of AlF3, AlO(OH) species(.) This approach provides an easy access to 2-aryl or 2-thio aryl pyrrolo[2,1-a]isoquinolines in good yields in a tandem fashion. With suitable ratio of gamma-Al2O3/TfOH binary system, the Michael addition of N/C/S nucleophiles to N-benzyl maleimide is also achieved. A key to the success of these reactions would be the generation of AlF3, AlO(OH) species from gamma-Al2O3 and TfOH, which might have delineated the disadvantageous background reactions usually displayed by a strong Bronsted acid such as TfOH.</p>},
	keywords = {1-a]isoquinolines, 3-substituted pyrrolidine-2, 5-diones, carbocyclization, gamma-Al2O3/TfOH binary system, Michael addition, pyrrolo[2},
	issn = {0022-152X},
	doi = {10.1002/jhet.4266, Early Access Date = APR 2021},
	author = {Rao, Ramana Sreenivasa and Sahani, Anita and Ali, Sheikh Haider and Pradhan, Sumanta and Ramanathan, Chinnasamy Ramaraj}
}
