@article { ISI:000343018200079,
	title = {Enhancing cubosome functionality by coating with a single layer of poly-epsilon-lysine},
	journal = {ACS Applied Materials \& Interfaces},
	volume = {6},
	number = {19},
	year = {2014},
	month = {OCT},
	pages = {17126-17133},
	publisher = {AMER CHEMICAL SOC},
	type = {Article},
	address = {1155 16TH ST, NW, WASHINGTON, DC 20036 USA},
	abstract = {<p>We report the preparation and characterization of monoolein cubosomes that can be easily surface modified through adsorption of a single layer of cationic poly-epsilon-lysine. Poly-epsilon-lysine coated cubosomes show remarkable stability in serum solution, are nontoxic and, are readily internalized by HeLa cells. The poly-epsilon-lysine coating provides chemical handles for further bioconjugation of the cubosome surface. We also demonstrate that the initial release rate of a hydrophilic drug, Naproxen sodium, from the cubosomes is retarded with just a single layer of polymer. Interestingly, cubosomes loaded with Naproxen sodium, recently shown to have anticancer properties, cause more apoptosis in HeLa cells when compared to free unencapsulated drug.</p>},
	keywords = {bioconjugation, cubosomes, drug delivery vehicle, dual loading, theranostics},
	issn = {1944-8244},
	doi = {10.1021/am5047872},
	author = {Deshpande, Sonal and Venugopal, Edakkal and Ramagiri, Shobha and Bellare, Jayesh R. and Kumaraswamy, Guruswamy and Singh, Neetu}
}
@article { ISI:000332782600001,
	title = {Extracellular biosynthesis of gadolinium oxide (Gd2O3) nanoparticles, their biodistribution and bioconjugation with the chemically modified anticancer drug taxol},
	journal = {Beilstein Journal of Nanotechnology},
	volume = {5},
	year = {2014},
	month = {MAR},
	pages = {249-257},
	publisher = {BEILSTEIN-INSTITUT},
	type = {Article},
	address = {TRAKEHNER STRASSE 7-9, FRANKFURT AM MAIN, 60487, GERMANY},
	abstract = {<p>As a part of our programme to develop nanobioconjugates for the treatment of cancer, we first synthesized extracellular, protein-capped, highly stable and well-dispersed gadolinium oxide (Gd2O3) nanoparticles by using thermophilic fungus Humicola sp. The biodistribution of the nanoparticles in rats was checked by radiolabelling with Tc-99m. Finally, these nanoparticles were bioconjugated with the chemically modified anticancer drug taxol with the aim of characterizing the role of this bioconjugate in the treatment of cancer. The biosynthesized Gd2O3 nanoparticles were characterized by UV-vis spectroscopy, transmission electron microscopy (TEM), X-ray diffraction (XRD) and X-ray photoemission spectroscopy (XPS). The Gd2O3-taxol bioconjugate was confirmed by UV-vis spectroscopy and fluorescence microscopy and was purified by using high performance liquid chromatography (HPLC).</p>},
	keywords = {bioconjugation, biodistribution, gadolinium oxide, humicola sp, transmission electron microscopy},
	issn = {2190-4286},
	doi = {10.3762/bjnano.5.27},
	author = {Khan, Shadab Ali and Gambhir, Sanjay and Ahmad, Absar}
}
