@article {49898,
	title = {Formal Synthesis of Corynanthe Indole Alkaloid ({\textpm})-Mitralactonine: Construction of α-Hydroxy-Keto Functionalized Tetracyclic Skeleton},
	journal = {Chemistryselect},
	volume = {10},
	year = {2025},
	month = {DEC },
	pages = {e04415},
	type = {Article},
	abstract = {<p>
	An efficient synthesis of a tetracyclic skeleton common to many corynanthe alkaloids was accomplished in 10 linear steps starting from a known tetrahydro beta-carboline intermediate. The tetracyclic alpha-hydroxy keto functionalized advanced precursor of (+/-)-mitralactonine was realized using Wittig olefination, ketohydroxylation of a trisubstituted alkene, and a tandem amine unmasking-intramolecular nucleophilic displacement reaction for C-N bond formation of C/D-rings.</p>
},
	keywords = {alpha-hydroxy keto, beta-carboline, corynanthe alkaloid, intramolecular N-alkylation, mitragynine},
	issn = {2365-6549},
	doi = {10.1002/slct.202504415},
	author = {Dumare, Nilesh B. and Sharma, Pallavi and Sivappa, Rasapalli and Chavan, Subhash P.}
}
@article {50040,
	title = {H5IO6, as an efficient reagent for the aromatization of tetrahydro-β-carbolines: total synthesis of norharman, harmane, harmine, kumujian-C, and orthoscuticellines B},
	journal = {ChemistrySelect},
	volume = {11},
	year = {2026},
	month = {MAR},
	pages = {e04252},
	type = {Article},
	abstract = {<p>
	A new method is reported for the synthesis of beta-carbolines and their derivatives using H5IO6 in DMSO solvent. The method is mild and efficient for oxidative decarboxylation and aromatization of tetrahydro beta-carbolines (TH beta C), resulting in good to excellent yields (70\% to 88\%) of beta-carbolines. This protocol has further been utilized for the synthesis of beta-carbolines based natural products, for examples, norharmane, harmane, harmine, Kumujian-C, and Orthoscuticellines A and B.</p>
},
	keywords = {aromatization, beta-carboline, H5IO6, Harmine, orthoscuticellines, Oxidative},
	issn = {2365-6549},
	doi = {10.1002/slct.202504252},
	author = {Sabane, Jagjivan K. and Gaikwad, Sunil V. and Gajbhiye, Jayant M. and Kumar, Pradeep}
}
