@article { ISI:000261921400006,
	title = {Proline-catalyzed simple and efficient synthesis of 1,8-dioxo-decahydroacridines in aqueous ethanol medium},
	journal = {Synthetic Communications},
	volume = {39},
	number = {2},
	year = {2009},
	month = {DEC},
	pages = {PII 907127919},
	publisher = {TAYLOR \& FRANCIS INC},
	address = {325 CHESTNUT ST, SUITE 800, PHILADELPHIA, PA 19106 USA},
	abstract = {<p>Proline-catalyzed synthesis of 1,8-dioxo-decahydroacridines is achieved via one-pot, three-component condensation of aromatic aldehydes, cyclic diketone, and aryl amines in aqueous ethanol medium. This method offers the advantages of proceeding in neutral and mild conditions, giving high to excellent yields of acridines with easy workup procedure.</p>},
	keywords = {1, 8-dioxodecahydroacridines, aqueous media, one-pot MCR, Proline},
	issn = {0039-7911},
	doi = {10.1080/00397910802044306},
	author = {Venkatesan, K. and Pujari, Suresh S. and Srinivasan, Kumar V.}
}
@article { ISI:000348245000002,
	title = {Comprehensive study on the effect of acid additives in 1(R),2(R)-Bis[(S)-prolinamido]cyclohexane catalyzed direct asymmetric aldol reactions in aqueous media},
	journal = {Indian Journal of Chemistry Section B-Organic Chemistry Including Medicinal Chemistry},
	volume = {54},
	number = {1},
	year = {2015},
	month = {JAN},
	pages = {84-92},
	publisher = {COUNCIL SCIENTIFIC \& INDUSTRIAL RES},
	address = {ANUSANDHAN BHAWAN, 2 RAFI MARG, NEW DELHI, 110001, INDIA},
	abstract = {<p>The catalytic efficacy of (1R,2R)-bis[(S)-prolinamido]cyclohexane 1, prepared from the readily available natural amino acid L-proline has been studied for the direct asymmetric aldol reaction of cyclohexanone with substituted benzaldehydes at room temperature in presence of various acid additives. A wide variety of acids e.g. aliphatic fatty acid, chiral acid, sulphonic acid, aromatic acid, etc. have been used as additive for the aldol reaction in aqueous media. A loading of 10 mol\% of catalyst 1 is employed in this reaction, and good yields (up to 98\% yield), diastereoselectivity (up to 96\% de) and enantioselectivities (up to 87\% ee) can be achieved in aqueous media within very short reaction time (1-4 hours).</p>},
	keywords = {acid additives, aqueous media, Asymmetric synthesis, direct aldol reaction, organocatalysis},
	issn = {0376-4699},
	author = {Bhowmick, Sudipto and Kunte, Sunita S. and Bhowmick, Kartick C.}
}
