@article {47396,
	title = {Nickel-catalyzed difunctionalization of alkynyl bromides with thiosulfonates and N-arylthio succinimides: a convenient synthesis of 1,2-thiosulfonylethenes and 1,1-dithioethenes},
	journal = {Synthesis-Stuttgart},
	year = {2021},
	month = {APR },
	type = {Article; Early Access},
	abstract = {<p>An efficient nickel-catalyzed vicinal thiosulfonylation of 1bromoalkynes with thiosulfonates in the presence of cesium carbonate is described. An operationally simple and highly regioselective atom transfer radical addition (ATRA) of alkynyl bromides provides a wide range of (E)-1,2-thiosulfonylethenes (alpha-aryl-beta-thioarylvinyl sulfones) in moderate to high yields. The extensive substrate scope of both alkynyl bromides and thiosulfonates is explored with a broad range of functional groups. Indole-derived 1,1- bromoalkenes were also successfully explored in this 1,2-thiosulfonylation process. Moreover, the nickel-catalyzed geminal- dithiolation of alkynyl bromides with N-arylthio succinimides provides 1,1-dithioalkenes in high yields. The present protocol is reliable on gram scale, and a sequential one-pot bromination and thiosulfonylation of phenylacetylene is achieved in a scale-up synthesis. Following control experiments, a plausible mechanism is proposed to rationalize the experimental outcome and the vicinal thiosulfonylation.</p>},
	keywords = {alkynyl bromides, atom transfer radical addition (ATRA), thiosulfonates, thiosulfonylation, vinyl thiosulfones},
	issn = {0039-7881},
	doi = {10.1055/a-1482-2486, Early Access Date = APR 2021},
	author = {Kumari, Arram Haritha and Kumar, Jangam Jagadesh and Krishna, Gamidi Rama and Reddy, Raju Jannapu}
}
@article {47599,
	title = {Interrupted CuAAC-thiolation for the construction of 1,2,3-triazole-fused eight-membered heterocycles from O-/N-propargyl derived benzyl thiosulfonates with organic azides},
	journal = {Advanced Synthesis \& Catalysis},
	volume = {364},
	year = {2022},
	month = {JAN},
	pages = {319-325},
	type = {Article},
	abstract = {A copper(I)-catalyzed interrupted click-sulfenylation of O-/N-propargyl benzyl thiosulfonates with organic azides has been disclosed. The unified CuAAC-thiolation provides a wide range of triazole-fused eight-membered heterocycles in good to high (51-94\%) yields under mild reaction conditions. Moreover, a three-component reaction is also achieved involving O-/N-propargyl benzyl thiosulfonates, benzyl bromide, and sodium azide to deliver fused-triazoles in 61-74\% yields. From a synthetic point of view, the present protocol has been demonstrated at gram-scale reactions. A plausible mechanism is also proposed based on experimental results and control experiments.},
	keywords = {Eight-Membered Heterocycles, Fused-Triazoles, Interrupted-Click Reaction, Thiolation, thiosulfonates},
	issn = {1615-4150},
	doi = {10.1002/adsc.202101256},
	author = {Reddy, Raju Jannapu and Waheed, Md and Kumari, Arram Haritha and Krishna, Gamidi Rama}
}
