@article { ISI:000230522300022,
	title = {Quantitative method for normalization of transfection efficiency using enhanced green fluorescent protein},
	journal = {Analytical Biochemistry},
	volume = {342},
	number = {2},
	year = {2005},
	month = {JUL},
	pages = {341-344},
	publisher = {ACADEMIC PRESS INC ELSEVIER SCIENCE},
	type = {Article},
	address = {525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 USA},
	issn = {0003-2697},
	doi = {10.1016/j.ab.2005.02.006},
	author = {Dandekar, D. H. and Kumar, M. and Ladha, J. S. and Ganesh, Krishna N. and Mitra, Debashis}
}
@article { ISI:000236979100030,
	title = {Amino functionalized novel cholic acid derivatives induce HIV-1 replication and syncytia formation in T cells},
	journal = {Journal of Medicinal Chemistry},
	volume = {49},
	number = {8},
	year = {2006},
	month = {APR},
	pages = {2652-2655},
	publisher = {AMER CHEMICAL SOC},
	type = {Article},
	address = {1155 16TH ST, NW, WASHINGTON, DC 20036 USA},
	abstract = {<p>Synthesis of C-11 azido/amino functionalized cholic acid derivatives has been achieved in excellent yields. Contrary to the previous prediction of analogous compounds to be HIV-1 protease inhibitors, in the present study these novel cholic acid derivatives induced host cell fusion during the progress of HIV-1 infection and produced multinucleated giant cells. This is the first report of syncytia induction and enhancement of viral replication in HIV-1 infected T cells by cholic acid derivatives.</p>},
	issn = {0022-2623},
	doi = {10.1021/jm051114u},
	author = {Salunke, Deepak B. and Ravi, D. S. and Pore, V. S. and Mitra, Debashis and Hazra, Braja G.}
}
@article {45390,
	title = {Design, synthesis, docking studies and biological screening of 2-thiazolyl substituted-2,3-dihydro-1H-naphtho[1,2-e][1,3]oxazines as potent HIV-1 reverse transcriptase inhibitors},
	journal = {European Journal of Medicinal Chemistry},
	volume = {157},
	year = {2018},
	month = {SEP},
	pages = {310-319},
	type = {Article},
	abstract = {1,3-oxazine nucleus and thiazolyl group features prominently in many biologically important natural products as well as bioactive molecules. A series of novel 2-thiazolyl substituted-2,3-dihydro-1H-naphtho [1,2-e][1,3]oxazine derivatives were designed and synthesized based on their structure-activity relationships (SARs) from 2-naphthol, substituted thiazolyl amines and formalin through ring closure by one-pot three component reaction. These derivatives were first evaluated for their inhibitory effect on HIV-1 Reverse Transcriptase (RT) enzyme activity. Out of 14 compounds, 4 showed potent inhibition of HIV-1 RT activity at significantly low concentration. Docking studies of these molecules revealed their high affinity binding to several amino acids of HIV-1 RT which are less sensitive to point mutations. Furthermore, anti-HIV activity of these molecules was analysed in a CD4(+) T cell-line, which indicates that Therapeutic Index (TI) of some of these compounds is better than Zidovudine and Efavirenz, known HIV-1 RT inhibitors. Taken together, our studies report for the first time some novel naphthoxazine derivatives with significant TI, which is through inhibition of HIV-1 RT activity. (C) 2018 Elsevier Masson SAS. All rights reserved.},
	doi = {10.1016/j.ejmech.2018.07.067},
	author = {Gawali, Rakhi and Trivedi, Jay and Bhansali, Sujit and Bhosale, Raghunath and Sarkar, Dhiman and Mitra, Debashis}
}
