@article { ISI:000227246800051,
	title = {Diastereoselective amidoalkylation of (3S,7aR)-6-benzyl-7-hydroxy-3-phenyltetra-hydro-5H-imidazo[1,5-c][1, 3]thiazol-5-one : a short and highly efficient synthesis of (+)-biotin},
	journal = {Journal of Organic Chemistry},
	volume = {70},
	number = {5},
	year = {2005},
	month = {MAR},
	pages = {1901-1903},
	publisher = {AMER CHEMICAL SOC},
	type = {Article},
	address = {1155 16TH ST, NW, WASHINGTON, DC 20036 USA},
	abstract = {<p>A short and highly efficient synthesis of W-biotin in 10 steps with 20\% overall yield has been achieved from L-cysteine involving amidoalkylation of hydroxy imidazothiazolone 4 via an acyliminium ion intermediate to furnish C-7-substituted imidazothiazolones 5b as the key step.</p>},
	issn = {0022-3263},
	doi = {10.1021/jo0488107},
	author = {Chavan, Subhash P. and Chittiboyina, A. G. and Ravindranathan, T. and Kamat, Subhash K. and Kalkote, Uttam R.}
}
@article { ISI:000231782100007,
	title = {Unusual stereochemical outcome of radical cyclization: synthesis of (+)-biotin},
	journal = {Tetrahedron},
	volume = {61},
	number = {39},
	year = {2005},
	month = {SEP},
	pages = {9273-9280},
	publisher = {PERGAMON-ELSEVIER SCIENCE LTD},
	type = {Article},
	address = {THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND},
	abstract = {<p>An enantioselective synthesis of (+)-biotin 1 starting from naturally available cysteine is described. The key steps are the unusual stereochemical outcome of radical cyclization of compound 10 to prepare 5,5-fused system 11, and the introduction of C4-sidechain at C-6 in 13 via a Grignard reaction. (c) 2005 Elsevier Ltd. All rights reserved.</p>},
	keywords = {biotin, exocyclization, radical cyclization},
	issn = {0040-4020},
	doi = {10.1016/j.tet.2005.07.070},
	author = {Chavan, Subhash P. and Chittiboyina, A. G. and Ramakrishna, G. and Tejwani, R. B. and Ravindranathan, T. and Kamat, Subhash K. and Rai, B. and Sivadasan, L. and Balakrishnan, K. and Ramalingam, S. and Deshpande, V. H.}
}
