@article { ISI:000229553300007,
	title = {Larvicidal activity of acacia nilotica extracts and isolation of D-pinitol - a bioactive carbohydrate},
	journal = {Chemistry \& Biodiversity},
	volume = {2},
	number = {5},
	year = {2005},
	month = {MAY},
	pages = {684-688},
	publisher = {VERLAG HELVETICA CHIMICA ACTA AG},
	type = {Article},
	address = {HOFWIESENSTRASSE 26, POSTFACH, CH-8042 ZURICH, SWITZERLAND},
	abstract = {<p>A low-molecular-weight, sugar-like compound other than glucose, fructose, sucrose, or myo-inositol showing lipophilic nature was isolated from the EtOH extract of Acacia nilotica. The structure of the compound was determined by spectral methods. This alicyclic polyalcohol was found to be D-pinitol (- 3-O-methyl-D-chiro-inositol; 1). The configuration of the compound was confirmed by single-crystal X-ray analysis. The compound I is known from Soybean, Australian mangroves, Fagonia indica, A rachis hypogaea, etc., but we have isolated this compound for the first time from the aerial parts of A. nilotica. Very few references have been cited for compound I for its entomological activity, and there are no reports on mosquitoes. Therefore, the crude extracts of A. nilotica were tested for its biological activity against mosquito larvae. Acetone extract at 500-ppm concentration showed chronic toxicity against Aedes aegypti and Culex quinquefasciatus IVth instar mosquito larvae. Such a biological activity has been observed for the first time for this plant. This study could be a stepping stone to a solution for destroying larval species as well as consumption of such a widely grown, problem weed, A. nilotica. This larvicidal agent, since it is derived from plant, is eco-friendly, cost effective, non-hazardous to nontarget organisms and would be safe unlike commercially available insecticides.</p>},
	issn = {1612-1872},
	doi = {10.1002/cbdv.200590044},
	author = {Chaubal, Rohini and Pawar, P. V. and Hebbalkar, G. D. and Tungikar, V. B. and Puranik, Vedavati G. and Deshpande, V. H. and Deshpande, N. R.}
}
@article { ISI:000231782100007,
	title = {Unusual stereochemical outcome of radical cyclization: synthesis of (+)-biotin},
	journal = {Tetrahedron},
	volume = {61},
	number = {39},
	year = {2005},
	month = {SEP},
	pages = {9273-9280},
	publisher = {PERGAMON-ELSEVIER SCIENCE LTD},
	type = {Article},
	address = {THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND},
	abstract = {<p>An enantioselective synthesis of (+)-biotin 1 starting from naturally available cysteine is described. The key steps are the unusual stereochemical outcome of radical cyclization of compound 10 to prepare 5,5-fused system 11, and the introduction of C4-sidechain at C-6 in 13 via a Grignard reaction. (c) 2005 Elsevier Ltd. All rights reserved.</p>},
	keywords = {biotin, exocyclization, radical cyclization},
	issn = {0040-4020},
	doi = {10.1016/j.tet.2005.07.070},
	author = {Chavan, Subhash P. and Chittiboyina, A. G. and Ramakrishna, G. and Tejwani, R. B. and Ravindranathan, T. and Kamat, Subhash K. and Rai, B. and Sivadasan, L. and Balakrishnan, K. and Ramalingam, S. and Deshpande, V. H.}
}
