@article { ISI:000231661800013,
	title = {Expeditious convergent synthesis of a dibromotyrosine alkaloid inhibitor of mycothiol-S-conjugate amidase},
	journal = {Tetrahedron Letters},
	volume = {46},
	number = {38},
	year = {2005},
	month = {SEP},
	pages = {6461-6463},
	publisher = {PERGAMON-ELSEVIER SCIENCE LTD},
	type = {Article},
	address = {THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND},
	abstract = {<p>A quick, economic synthesis of the alkaloid 1, an inhibitor of mycothiol-S-conjugate amidase (MCA) is reported. Starting from low-cost, commercially available 4-hydroxybenzaldehyde, the nine-step synthesis involved dibromination and coupling with N-acetylglycine to give a stable methyloxazole intermediate 5 which was hydrolyzed, oximated and coupled to agmatine to yield the oxime in -30\% overall yield. It was not necessary to protect the oxime in the synthetic sequence thereby circumventing a deprotection step. (c) 2005 Elsevier Ltd. All rights reserved.</p>},
	keywords = {4-hydroxybenzaldehyde, marine alkaloid, mycothiol-S-conjugate amidase},
	issn = {0040-4039},
	doi = {10.1016/j.tetlet.2005.07.109},
	author = {Chanda, B. M. and Sulake, R. S.}
}
