@article { ISI:000350657700011,
	title = {Role of structure and entropy in determining differences in dynamics for glass formers with different interaction potentials},
	journal = {Physical Review Letters},
	volume = {113},
	number = {22},
	year = {2014},
	month = {NOV},
	pages = {225701},
	publisher = {AMER PHYSICAL SOC},
	address = {ONE PHYSICS ELLIPSE, COLLEGE PK, MD 20740-3844 USA},
	abstract = {<p>We present a study of two model liquids with different interaction potentials, exhibiting similar structure but significantly different dynamics at low temperatures. By evaluating the configurational entropy, we show that the differences in the dynamics of these systems can be understood in terms of their thermodynamic differences. Analyzing their structure, we demonstrate that differences in pair correlation functions between the two systems, through their contribution to the entropy, dominate the differences in their dynamics, and indeed overestimate the differences. Including the contribution of higher order structural correlations to the entropy leads to smaller estimates for the relaxation times, as well as smaller differences between the two studied systems.</p>},
	issn = {0031-9007},
	doi = {10.1103/PhysRevLett.113.225701},
	author = {Banerjee, Atreyee and Sengupta, Shiladitya and Sastry, Srikanth and Bhattacharyya, Sarika Maitra}
}
@article { ISI:000373762400005,
	title = {Reporter nanoparticle that monitors its anticancer efficacy in real time},
	journal = {Proceedings of the National Academy of Sciences of the United States of America},
	volume = {113},
	number = {15},
	year = {2016},
	month = {APR},
	pages = {E2104-E2113},
	publisher = {NATL ACAD SCIENCES},
	address = {2101 CONSTITUTION AVE NW, WASHINGTON, DC 20418 USA},
	abstract = {<p>The ability to monitor the efficacy of an anticancer treatment in real time can have a critical effect on the outcome. Currently, clinical readouts of efficacy rely on indirect or anatomic measurements, which occur over prolonged time scales postchemotherapy or postimmunotherapy and may not be concordant with the actual effect. Here we describe the biology-inspired engineering of a simple 2-in-1 reporter nanoparticle that not only delivers a cytotoxic or an immunotherapy payload to the tumor but also reports back on the efficacy in real time. The reporter nanoparticles are engineered from a novel two-staged stimuli-responsive polymeric material with an optimal ratio of an enzyme-cleavable drug or immunotherapy (effector elements) and a drug function-activatable reporter element. The spatiotemporally constrained delivery of the effector and the reporter elements in a single nanoparticle produces maximum signal enhancement due to the availability of the reporter element in the same cell as the drug, thereby effectively capturing the temporal apoptosis process. Using chemotherapy-sensitive and chemotherapy-resistant tumors in vivo, we show that the reporter nanoparticles can provide a real-time noninvasive readout of tumor response to chemotherapy. The reporter nanoparticle can also monitor the efficacy of immune checkpoint inhibition in melanoma. The self-reporting capability, for the first time to our knowledge, captures an anticancer nanoparticle in action in vivo.</p>},
	keywords = {chemotherapy, immunotherapy, monitoring, nanoparticle, reporter},
	issn = {0027-8424},
	doi = {10.1073/pnas.1603455113},
	author = {Kulkarni, Ashish and Rao, Poornima and Natarajan, Siva and Goldman, Aaron and Sabbisetti, Venkata S. and Khater, Yashika and Korimerla, Navya and Chandrasekar, Vineethkrishna and Mashelkar, Raghunath Anant and Sengupta, Shiladitya}
}
