@article { ISI:000367840900002,
	title = {Interfacial tension approach toward drug loading with two-dimensional crosslinked polymer embedded gold: adsorption kinetics evaluation},
	journal = {International Journal Of Polymeric Materials And Polymeric Biomaterials},
	volume = {65},
	number = {4},
	year = {2016},
	month = {JAN},
	pages = {168-175},
	publisher = {TAYLOR \& FRANCIS AS},
	address = {KARL JOHANS GATE 5, NO-0154 OSLO, NORWAY},
	abstract = {<p>Interfacial tension of drugs with hydrophilic polymer (A) embedded gold resulting into selective drug adsorption, which also affected the drug adsorption kinetics. Two-dimensional crosslinked polymer embedded gold was synthesized for drug loading application in an acidic buffer. Lower interfacial tension of pantoprazole sodium (B) revealed the exponential loading inversely loading was gradual for chloroquine (C) having more interfacial tension with adsorbent. Initial 2 h was the exponential adsorption period for a pantoprazole sodium whereas exponential adsorption begins after 12 h for a chloroquine. Monolayer drug adsorption was obtained because Langmuir adsorption isotherm was obeyed by both drugs. Moreover, pseudo first-and pseudo second-order kinetics was also evaluated which demonstrated that reactive sites of the adsorbent are homogeneous and drug adsorption mechanism is chemisorption and not the physisorption. Thermal analysis was evaluated to confirm the polymer thermostability and glass transition temperature during catalytic applications in thermal reactions.</p>},
	keywords = {Adsorption isotherm, adsorption kinetics, drug loading, drug polarity, Interfacial tension},
	issn = {0091-4037},
	doi = {10.1080/00914037.2015.1074911},
	author = {Mane, Sachin and Ponrathnam, Surendra and Chavan, Nayaku}
}
@article { ISI:000367940900010,
	title = {Inverse high internal phase emulsion polymerization (i-HIPE) of GMMA, HEMA and GDMA for the preparation of superporous hydrogels as a tissue engineering scaffold},
	journal = {Journal of Materials Chemistry B},
	volume = {4},
	number = {3},
	year = {2016},
	month = {NOV},
	pages = {450-460},
	publisher = {ROYAL SOC CHEMISTRY},
	address = {THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND},
	abstract = {<p>A series of novel superporous hydrogels for regenerative medicine were prepared by oil-in-water (o/w) or inverse high internal phase emulsion (i-HIPE) copolymerization of glycerol monomethacrylate (GMMA), 2-hydroxy ethyl methacrylate (HEMA) and glycerol dimethacrylate (GDMA) as a cross-linker using a non toxic solvent and a redox initiator system at the physiological temperature (37 degrees C). The monomer GMMA was synthesized from glycidyl methacrylate (GMA) by an alternative facile method using Amberlyst-15. The described i-HIPEs showed a significantly wider stability window. The polyHIPE hydrogels were characterized by FTIR, BET method for surface area, mercury porosimetry, SEM, DSC, TGA, XRD, compressive strain and strain recovery. The swelling ratio of the hydrogels and their degradation in 0.007 M NaOH and lipase B (Candida antarctica) solutions were determined gravimetrically and the rate of degradation was explained in terms of the molecular structure of the hydrogels. The morphological studies showed that the pore diameter varied between 20 and 30 mu m and the pore throats (interconnecting windows) diameter was in the range of 4-8 mu m. The described polyHIPE hydrogels were found to have an open cell morphology and interconnected pore architecture, which are important characteristics for scaffold applications. The initial cytotoxicity study performed according to ISO-10993-5 indicated cytocompatibility (97\% cell viability) and the subsequent cell seeding and proliferation study exhibited 55-88\% cell viability (increased monotonously from GHG-1 to GHG-5), which could be attributed to modulation of the physical and chemical properties of the hydrogels. The described super porous hydrogels are considered as potential candidates for scaffold materials in tissue engineering applications.</p>},
	issn = {2050-750X},
	doi = {10.1039/c5tb01873k},
	author = {Nalawade, Archana C. and Ghorpade, Ravindra V. and Shadbar, Sadiqua and Qureshi, Mohammed Shadbar and Chavan, Nayaku and Khan, Ayesha A. and Ponrathnam, S.}
}
