@article { ISI:000237126200010,
	title = {Cyclitol based metal complexing agents. preference for the extraction of lithium by myo-inositol based crown-4-ethers depends on the relative orientation of crown ether oxygen atoms},
	journal = {Tetrahedron},
	volume = {62},
	number = {18},
	year = {2006},
	month = {MAY},
	pages = {4360-4363},
	publisher = {PERGAMON-ELSEVIER SCIENCE LTD},
	type = {Article},
	address = {THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND},
	abstract = {<p>myo-Inositol derived crown-4-ethers in which two of the oxygen atoms in the crown ether moiety have different relative orientations were prepared. Metal picrate binding studies revealed that the crown ether having 1,3-diaxial orientation shows the highest selectivity for binding to lithium although the crown ether having 1,2-diequatorial orientation exhibited the highest binding constant for lithium picrate. These results suggest that relative binding affinity of metal ions to crown ethers can be tuned by varying the relative orientation of crown ether oxygen atoms. The relevance of these results to the previously observed regioselectivity during the O-substitution of myo-inositol orthoesters is discussed. (c) 2606 Elsevier Ltd. All rights reserved.</p>},
	keywords = {crown ether, Cyclitol, Inositol, ligand, lithium, metal complex},
	issn = {0040-4020},
	doi = {10.1016/j.tet.2006.02.075},
	author = {Dixit, Shailesh S. and Shashidhar, M. S. and Devaraj, Subramanian}
}
@article { ISI:000253515100019,
	title = {Inositol derived crown ethers: effect of auxiliary protecting groups and the relative orientation of crown ether oxygen atoms on their metal ion binding ability},
	journal = {Tetrahedron},
	volume = {64},
	number = {9},
	year = {2008},
	month = {FEB},
	pages = {2160-2171},
	publisher = {PERGAMON-ELSEVIER SCIENCE LTD},
	type = {Article},
	address = {THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND},
	abstract = {<p>The binding constants of crown ethers prepared from tetra-O-substituted myo- and scyllo-inositol derivatives and 2-O-substituted myo- and scyllo-inositol-1,3,5-orthoformates, with metal picrates show that the O-substituents and the relative orientation of the crown ether oxygen atoms contribute significantly to the binding of crown ethers with metal ions. In particular, the binding efficiency of myo-inositol derived crown ethers to silver and potassium ions could be enhanced by introducing benzyl ethers in the inositol ring. Hence binding efficacy and selectivity of metal ions to inositol derived crown ethers can be tuned by varying substituents on the myo-inositol ring and/or the relative orientation of crown ether oxygen atoms. (C) 2007 Elsevier Ltd. All rights reserved.</p>},
	keywords = {crown ether, Cyclitol, Inositol, ligand, metal complex, supramolecule},
	issn = {0040-4020},
	doi = {10.1016/j.tet.2007.12.034},
	author = {Dixit, Shailesh S. and Shashidhar, Mysore S.}
}
