@article { ISI:000366209800015,
	title = {Synthesis of 3-Thia-1-dethiacephems via Regioselective Iodocyclization Reaction},
	journal = {Synthesis-Stuttgart},
	volume = {47},
	number = {24},
	year = {2015},
	month = {DEC},
	pages = {3956-3962},
	publisher = {GEORG THIEME VERLAG KG},
	address = {RUDIGERSTR 14, D-70469 STUTTGART, GERMANY},
	abstract = {<p>The key N-homopropargylthiourea intermediates, N-substituted 2-oxo-4-propargylazetidine-1-carbothioamides, were prepared by the reaction of a 4-propargylazetidin-2-one with isothiocyanates. Bicyclic -lactams, i.e. 3-thia-1-dethiacephems, were prepared via highly regioselective iodocyclization reaction of N-substituted 2-oxo-4-propargylazetidine-1-carbothioamides with molecular iodine at room temperature in moderate to excellent yields. A variety of functional groups were well tolerated under the reaction conditions.</p>},
	keywords = {-lactams, 3-thia-1-dethiacephems, Iodocyclization, Regioselective, thiourea},
	issn = {0039-7881},
	doi = {10.1055/s-0035-1560350},
	author = {Garud, Dinesh R. and Rode, Navnath D. and Bathe, Sagar R. and Ranpise, Vinod S. and Joshi, Ramesh A. and Joshi, Rohini R. and Koketsu, Mamoru}
}
