@article { ISI:000239179300033, title = {Enantioselective synthesis of (+)-(S,S)-reboxetine}, journal = {Synlett}, number = {11}, year = {2006}, month = {JUL}, pages = {1771-1773}, publisher = {GEORG THIEME VERLAG KG}, type = {Article}, address = {RUDIGERSTR 14, D-70469 STUTTGART, GERMANY}, abstract = {

An efficient enantioselective synthesis leading directly to (+)-(S,S)-reboxetine has been described from commercially available trans-cinnammyl bromide using Sharpless asymmetric dihydroxylation as the key step.

}, keywords = {coupling, Dihydroxylation, Hydrogenation, reboxetine, trans-cinnamyl bromide}, issn = {0936-5214}, doi = {10.1055/s-2006-944210}, author = {Siddiqui, Shafi A. and Narkhede, Umesh C. and Lahoti, Rajgopal J. and Srinivasan, Kumar V.} } @article { ISI:000252094200024, title = {Efficient synthesis of 2,4-disubstituted thiazoles using ionic liquid under ambient conditions: a practical approach towards the synthesis of Fanetizole}, journal = {Tetrahedron }, volume = {63}, number = {45}, year = {2007}, month = {NOV}, pages = {11066-11069}, publisher = {PERGAMON-ELSEVIER SCIENCE LTD}, type = {Article}, address = {THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND}, abstract = {

A highly efficient and rapid synthesis of 2-amino-4-arylthiazoles and 2-methyl-4-arylthiazole from alpha-bromoketone and thiourea/thioamide is described using room temperature ionic liquid at ambient conditions. The method is simple, rapid and practical, generating thiazole derivatives in excellent isolated yields. This protocol is utilized for a commercially feasible synthesis of an anti-inflammatory agent, Fanetizole. (c) 2007 Published by Elsevier Ltd.

}, keywords = {alpha-bromo ketone, ionic liquids, thiazoles, thiourea/thioamide}, issn = {0040-4020}, doi = {10.1016/j.tet.2007.08.036}, author = {Potewar, Taterao M. and Ingale, Sachin A. and Srinivasan, Kumar V.} } @article { ISI:000250607100014, title = {Enantioselective synthesis of (S)-dapoxetine}, journal = {Tetrahedron-Asymmetry}, volume = {18}, number = {17}, year = {2007}, month = {SEP}, pages = {2099-2103}, publisher = {PERGAMON-ELSEVIER SCIENCE LTD}, type = {Article}, address = {THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND}, abstract = {

An efficient enantioselective synthesis leading directly to (+)-(S)-dapoxetine has been described for the first time using Sharpless asymmetric dihydroxylation, Barton-McCombie deoxygention, and Mitsunobu reaction as the key steps. (C) 2007 Published by Elsevier Ltd.

}, issn = {0957-4166}, doi = {10.1016/j.tetasy.2007.07.028}, author = {Siddiqui, Shafi A. and Srinivasan, Kumar V.} } @article { ISI:000260411100014, title = {Efficient and eco-friendly synthesis of 2-amino-1,3-selenazoles in an ionic liquid/water system under ambient conditions}, journal = {Arkivoc}, number = {12}, year = {2008}, month = {JAN}, pages = {117-125}, publisher = {ARKAT USA INC}, type = {Article}, address = {C/O ALAN R KATRITZKY, UNIV FLORIDA, DEPT CHEMISTRY, PO BOX 117200, GAINESVILLE, FL 32611 USA}, abstract = {

An efficient and eco-friendly synthesis of 2-amino-1,3-selenazoles in ionic liquid/water solvent system is described. The paper describes synthesis of 2-amino-1,3-selenazoles by condensation of various phenacyl bromide with selenourea under ambient conditions in short reaction times. This protocol has notable advantages such as the absence of any added catalyst, simple operation and excellent yields of products and recyclability of the ionic liquid.

}, keywords = {2-Amino-1, 3-selenazoles, ambient conditions, heterocycles, ionic liquid/water system, selenoureas, substituted phenacyl bromide}, issn = {1551-7004}, author = {Potewar, Taterao M. and Ingale, Sachin A. and Srinivasan, Kumar V.} } @article { ISI:000260290500013, title = {Efficient synthesis of antifungal pyrimidines via palladium catalyzed Suzuki/Sonogashira cross-coupling reaction from Biginelli 3,4-dihydropyrimidin-2(1H)-ones}, journal = {Tetrahedron}, volume = {64}, number = {44}, year = {2008}, month = {OCT}, pages = {10214-10223}, publisher = {PERGAMON-ELSEVIER SCIENCE LTD}, type = {Article}, address = {THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND}, abstract = {

An efficient regioselective approach to the synthesis of tetrasubstituted pyrimidines was developed by sequential functionalization of easily available Biginelli 3,4-dihydropyrimidine-2(1H)-ones via dehydrogenation, chlorination followed by palladium catalyzed C-C Suzuki/Sonogashira coupling reaction. All the synthesized compounds were evaluated in vitro for their antifungal activities against Candida albicans, Cryptococcus neoformans, Benjaminiella poitrasii, Yarrowia lipolytica, and Fusarium oxysporum, and antibacterial activities against Gram-negative Escherichia coli and Gram-positive Staphylococcus aureus. (c) 2008 Elsevier Ltd. All rights reserved.

}, keywords = {Antifungal activities, Biginelli compounds, chlorination, Oxidation, Pyrimidines, Suzuki coupling}, issn = {0040-4020}, doi = {10.1016/j.tet.2008.08.033}, author = {Gholap, Atul R. and Toti, Kiran S. and Shirazi, Fazal and Deshpande, Mukund V. and Srinivasan, Kumar V.} } @article { ISI:000260209800002, title = {Efficient synthesis of quinoxalines in the ionic liquid 1-n-butylimidazolium tetrafluoroborate ([Hbim]BF4) at ambient temperature}, journal = {Synthetic Communications}, volume = {38}, number = {21}, year = {2008}, month = {FEB}, pages = {3601-3612}, publisher = {TAYLOR \& FRANCIS INC}, type = {Article}, address = {325 CHESTNUT ST, SUITE 800, PHILADELPHIA, PA 19106 USA}, abstract = {

Quinoxaline derivatives have been synthesized in excellent yields using an ionic liquid (IL) (viz., 1-n-butylimidazolium tetrafluoroborate) as a reaction medium as well as promoter from various 1,2-diketones and aryl-1,2-diamines. The process is general for the synthesis of quinoxaline derivatives from aromatic as well as aliphatic-1,2-diketones. The advantages of the present method are ambient reaction temperature, simplicity of operation, high yields of products, the recyclability of the IL, and ecofriendly nature of the reaction medium.

}, keywords = {1, 2-diamines, 2-Diketones, Aryl-1, ionicliquid(IL), quinoxalines}, issn = {0039-7911}, doi = {10.1080/00397910802054271}, author = {Potewar, Taterao M. and Ingale, Sachin A. and Srinivasan, Kumar V.} }