@article { ISI:000249453100008,
	title = {4-Formylazetidin-2-one as a useful building block for the formal synthesis of xylo-(2S,3R,4R)-phytosphingosine and threo-(2S,3S)-sphingosine},
	journal = {Synthesis-Stuttgart },
	volume = {17},
	number = {17},
	year = {2007},
	month = {SEP},
	pages = {2631-2636},
	publisher = {GEORG THIEME VERLAG KG},
	type = {Article},
	address = {RUDIGERSTR 14, D-70469 STUTTGART, GERMANY},
	abstract = {<p>Stereoselective formal synthesis of xylo-(2S,3R,4R)-phytosphingosine and threo-(2S,3S)-sphingosine is described starting from an enantiopure formyl-substituted P-lactam. Grignard reaction of the N-Boc-protected-beta-lactam carbonyl group, followed by further transformations, provides a common intermediate for xylo-(2S,3R,4R)-phytosphingosine and threo-(2S,3S)-sphingosine.</p>},
	keywords = {azetidin-2-one, beta-lactam, Grignard reaction, Phytosphingosine, Sphingosine},
	issn = {0039-7881},
	doi = {10.1055/s-2007-983815},
	author = {Kale, Ajaykumar S. and Sakle, Prathmesh S. and Gumaste, Vikas K. and Deshmukh, Abdul Rakeeb A. S.}
}
@article { ISI:000244732800019,
	title = {Stereoselective synthesis of 3-alkylidene/alkylazetidin-2-ones from azetidin-2,3-diones},
	journal = {Tetrahedron},
	volume = {63},
	number = {11},
	year = {2007},
	month = {MAR},
	pages = {2524-2534},
	publisher = {PERGAMON-ELSEVIER SCIENCE LTD},
	type = {Article},
	address = {THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND},
	abstract = {<p>Azetidin-2,3-diones have been used as synthons for the synthesis of C-3 alkylidene/alkylazetidin-2-ones. Some of the 3-alkylazetidin-2-ones are well known for their cholesterol absorption inhibitor activity. A regio and stereoselective Grignard reaction on a keto group followed by dehydration using PPh3/CCl4 reagent is a key step in this synthesis. Hydrogenation of the 3-alkylideneazetidin-2-ones provided stereoselectively cis-3-alkylazetidin-2-ones in very good yields. (c) 2006 Published by Elsevier Ltd.</p>},
	keywords = {3-diones, azetidin-2, azetidin-2-ones, beta-lactam, Grignard reaction},
	issn = {0040-4020},
	doi = {10.1016/j.tet.2006.12.010},
	author = {Tiwari, Dharmendra Kumar and Shaikh, Ashif Y. and Pavase, Laxmikant S. and Gumaste, Vikas K. and Deshmukh, Abdul Rakeeb A. S.}
}
