@article { ISI:000232981200014, title = {Aziridine carboxylate from D-glucose: synthesis of polyhydroxylated piperidine, pyrrolidine alkaloids and study of their glycosidase inhibition}, journal = {Organic \& Biomolecular Chemistry}, volume = {3}, number = {20}, year = {2005}, month = {OCT}, pages = {3720-3726}, publisher = {ROYAL SOC CHEMISTRY}, type = {Article}, address = {THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND}, abstract = {

The D-glucose derived aziridine carboxylate 5 was obtained from (E)-ethyl-6-bromo-1,2-O-isopropylidene-3-O-benzyl-5-deoxy-alpha-D-xylo-5 -eno-heptofuranuronate 4 through conjugate addition of benzylamine and in situ intramolecular nucleophilic expulsion of bromine. The regioselective aziridine ring-opening, using water as a nucleophile, resulted in the alpha-hydroxy-beta-aminoester 6, which was exploited in the synthesis of six and five membered azasugars 1b/1c and 2b/2c, respectively The glycosidase inhibitory activity of the title compounds was evaluated.

}, issn = {1477-0520}, doi = {10.1039/b509216g}, author = {Dhavale, Dilip D. and Kumar, K. S. A. and Chaudhari, Vinod D. and Sharma, T. and Sabharwal, Sushma G. and PrakashaReddy, J.} } @article { ISI:000228412500017, title = {Structural rationalisation of co-crystals formed between trithiocyanuric acid and molecules containing hydrogen bonding functionality}, journal = {Chemistry - A European Journal}, volume = {11}, number = {8}, year = {2005}, note = {Symposium on Chemistry-A European Conference - Stimulating Concepts in Chemistry, Inst Sci Ingenierie Supramoleculaires, Strasbourg, FRANCE, APR 15, 2005}, month = {APR}, pages = {2433-2439}, publisher = {WILEY-BLACKWELL}, type = {Article}, address = {COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA}, abstract = {

Crystallisation of trithiocyanuric acid (TTCA) from various organic solvents that have hydrogen bonding capability (acetone, 2-butanone, dimethylformamide, dimethyl sulfoxide, methanol and acetonitrile) leads to the formation of co-crystals in which the solvent molecules are incorporated together with TTCA in the crystal structure. Structure determination by single-crystal X-ray diffraction reveals that these co-crystals can be classified into different groups depending upon the topological arrangement of the TTCA molecules in the crystal structure. Thus, three different types of single-tape arrangements of TTCA molecules and one type of double-tape arrangement of TTCA molecules are identified. In all co-crystals, hydrogen-bonding interactions are formed through the involvement of N-H bonds of TTCA molecules in these tapes and the other molecule in the co-crystal. Detailed rationalisation of the structural properties of these co-crystals is presented.

}, keywords = {crystal engineering, hydrogen bonds, nitrogen heterocycles, structure elucidation}, issn = {0947-6539}, doi = {10.1002/chem.200400340}, author = {Ahn, Sung-Hoon and PrakashaReddy, J. and Kariuki, B. M. and Chatterjee, S. and Ranganathan, A. and Pedireddi, V. R. and Rao, C. N. R. and Harris, Kenneth D. M.} } @article { ISI:000271838100014, title = {C-H center dot center dot center dot N hydrogen bonds mediated solid state structures of 2,2 {\textquoteleft}-bis (4-pyridylsulfanylmethyl)-1,1 {\textquoteleft}-biphenyl and 9-(4-pyridylsulfanyl)phenanthrene}, journal = {Journal of Molecular Structure}, volume = {937}, number = {1-3}, year = {2009}, month = {NOV}, pages = {81-84}, publisher = {ELSEVIER SCIENCE BV}, address = {PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS}, abstract = {

Solid state structure elucidation of sulfanyl ligands, 2,2{\textquoteright}-bis(4-pyridylsulfany[methyl)-1,1{\textquoteright}-biphenyl, L(1) and 9-(4-pyridylsulfanyl)plienanthrene, L(2) are reported. In the structures L(1) and L(2), the molecules are self-assembled through C-H center dot center dot center dot N hydrogen bonds, yielding ensembles of cyclic and helical networks. (C) 2009 Elsevier B.V. All rights reserved.

}, keywords = {hydrogen bonds, noncovalent interactions, Supramolecular assemblies}, issn = {0022-2860}, doi = {10.1016/j.molstruc.2009.08.020}, author = {Upadhye, Ketaki and PrakashaReddy, J. and Pedireddi, V. R.} }