@article { ISI:000246157400036,
	title = {Kinetics of reductive alkylation of p-phenylenediamine with methyl ethyl ketone using 3\% Pt/Al2O3 catalyst in a slurry reactor},
	journal = {Industrial \& Engineering Chemistry Research},
	volume = {46},
	number = {10},
	year = {2007},
	month = {MAY},
	pages = {3243-3254},
	publisher = {AMER CHEMICAL SOC},
	type = {Article},
	address = {1155 16TH ST, NW, WASHINGTON, DC 20036 USA},
	abstract = {<p>Intrinsic kinetics of reductive alkylation of p-phenylenediamine (PPDA) with methyl ethyl ketone (MEK) using 3\% Pt/Al2O3 catalyst was studied in a slurry reactor. The overall reaction involves a combination of parallel and consecutive reactions involving equilibrium noncatalytic (homogeneous) and catalytic (heterogeneous) steps. For the purpose of kinetic modeling, the effects of PPDA concentration, catalyst loading, agitation speed, and partial pressure of hydrogen were studied in a temperature range of 373-413 K. Quantitative criteria were used to ensure that the reaction occurred in the kinetic regime. Different rate equations have been considered based on the elementary steps involving catalytic and noncatalytic reactions, which lay stress on the different types of interactions occurring between the reactants and the active catalyst sites. The best-fit rate model has been proposed by rigorous optimization and model discrimination procedures, by simulating the experimental concentration-time data. For the best-fit model, the agreement between the predicted and experimental data was found to be very good over a wide range of operating conditions.</p>},
	issn = {0888-5885},
	doi = {10.1021/ie0608556},
	author = {Patil, Narendra G. and Roy, Debdut and Chaudhari, Amit S. and Chaudhari, Raghunath V.}
}
@article { ISI:000276206700037,
	title = {Kinetics of reductive alkylations of phenylenediamines: influence of substrates isomeric structure},
	journal = {Chemical Engineering Science},
	volume = {65},
	number = {1, SI},
	year = {2010},
	note = {20th International Symposium on Chemical Reaction Engineering, Kyoto, JAPAN, SEP, 2008},
	month = {JAN},
	pages = {232-239},
	publisher = {PERGAMON-ELSEVIER SCIENCE LTD},
	address = {THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND},
	abstract = {<p>Reductive alkylation of ortho-, meta- and para-phenylenediamines (PDAs) with methyl ethyl ketone (MEK) has been studied in a semi-batch slurry reactor in the presence of a commercial 3\% Pt/Al(2)O(3) catalyst. It was observed that the PDA isomers differ remarkably from each other in their activity in reductive alkylation and product distribution. The activity was found to decrease in the following order: PPDA \&gt; OPDA \&gt; MPDA. To understand the substrate structure-activity correlation, the homogeneous equilibrium reactions involved in the alkylation step and the overall catalytic reactions were studied separately. Kinetics of reductive alkylation of PDAs with MEK as a solvent and alkylating agent with 3\% Pt/Al(2)O(3) catalyst was studied in a semi-batch slurry reactor over a temperature range of 373-453K and pressure range of 2.07-6.21 MPa. Semi-batch slurry reactor models were developed and kinetic parameters were estimated by fitting the integral batch reactor data at different temperatures to understand the influence of different reaction steps on the activity and selectivity of different products. Published by Elsevier Ltd.</p>},
	keywords = {Batch, catalysis, kinetics, Multiphase reactions, Phenylenediamines, Reaction engineering, Reductive alkylation},
	issn = {0009-2509},
	doi = {10.1016/j.ces.2009.06.065},
	author = {Roy, Debdut and Chaudhari, Amit S. and Chaudhari, Raghunath V.}
}
