@article { ISI:000290685100004,
	title = {Diastereoselective synthesis of 1,1,4-trisubstituted-2,3,4,9-tetrahydrospiro-beta-carbolines via glacial acetic acid catalyzed pictet - spengler reaction},
	journal = {Arkivoc},
	number = {2},
	year = {2011},
	month = {OCT},
	pages = {41-56},
	publisher = {ARKAT USA INC},
	address = {C/O ALAN R KATRITZKY, UNIV FLORIDA, DEPT CHEMISTRY, PO BOX 117200, GAINESVILLE, FL 32611 USA},
	abstract = {<p>The Pictet-Spengler reaction of substituted tryptamines with cyclic ketones using glacial acetic acid afforded only one diastereomer of unreported 1,1,4-trisubstituted-2,3,4,9-tetrahydrospiro-beta-carbolines. The stereoselectivity in the reaction has been demonstrated using unsymmetrical ketones and single-crystal X-ray analysis of one of the spiro products in the form of base, its sulfate and hydrochloride salts, which indicated the formation of only the R, R diastereomer.</p>},
	keywords = {1, 3, 4, 4-Trisubstituted-2, 9-tetrahydrospiro-beta-carbolines, beta-substituted tryptamine, Diastereoselective Pictet-Spengler reaction, Glacial acetic acid},
	issn = {1551-7004},
	author = {Shumaila, Abdullah M. A. and Puranik, Vedavati G. and Kusurkar, Radhika S.}
}
