@article {BHONDE, title = {Clickable SBA-15 mesoporous materials: synthesis, characterization and their reaction with alkynes}, journal = {Journal of Materials Chemistry}, volume = {19}, number = {10}, year = {2009}, month = {JAN}, pages = {1409-1416}, publisher = {ROYAL SOC CHEMISTRY}, type = {Article}, address = {THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND}, abstract = {

SBA-15 mesoporous silica has been functionalized with azidopropyl groups through both one-pot co-condensation and post-synthetic grafting. For both these methodologies, azidopropyltriethoxysilane was used to introduce the azidopropyl groups. The azidopropyl modified SBA-15 material synthesized by one-pot co-condensation had hexagonal crystallographic order, pore diameters up of 50 angstrom, and the content of azidopropyl groups was found to be 1.3 mmol g(-1). The presence of the azidopropyl group was confirmed by multinuclear ((13)C, (29)Si) solid state NMR and IR spectroscopy. Both these materials underwent very efficient Cu(I)-catalyzed azide alkyne {\textquoteleft}{\textquoteleft}click{\textquoteright}{\textquoteright} reaction (CuAAC) with a variety of alkynes. Nearly 85\% of the azide present in the SBA-15 material was converted to the corresponding triazole when propargyl alcohol was used as the substrate. This methodology was also used to incorporate mannose into SBA-15. Incubation of this mannose labeled SBA-15 with fluorescein labeled Concanavalin-A led to the formation of a fluorescent silica-protein hybrid material. The ease of synthesis for the azide labeled SBA-15 material together with its ability to undergo very efficient chemoselective CuAAC in water would make it a very attractive platform for the development of covalently anchored catalysts, enzymes and sensors.

}, issn = {0959-9428}, doi = {10.1039/b815350g}, author = {Malvi, Bharmana and Sarkar, Bibhas R. and Pati, Debasis and Mathew, Renny and Ajithkumar, Thalasseril G. and Sen Gupta, Sayam} } @article { ISI:000294701600022, title = {Functionalization of SBA-15 mesoporous materials using {\textquoteleft}{\textquoteleft}thiol-ene click{\textquoteright}{\textquoteright} michael addition reaction}, journal = {Journal of Physical Chemistry C }, volume = {115}, number = {36}, year = {2011}, month = {SEP}, pages = {17774-17781}, publisher = {AMER CHEMICAL SOC}, address = {1155 16TH ST, NW, WASHINGTON, DC 20036 USA}, abstract = {

Methacrylate-labeled SBA-15 has been successfully synthesized from calcined SBA-15 and commercially available 3-trichlorosilyl propylmethacrylate. This material undergoes efficient thiol-ene {\textquoteleft}{\textquoteleft}click reaction{\textquoteright}{\textquoteright} with a variety of both thiol and disulfide-containing substrates in aqueous and organic media. The products were thoroughly characterized by a variety of analytical techniques including multinuclear (C-13, Si-29) solid-state NMR, TG-DTA, and nitrogen adsorption desorption studies. Disulfide-containing substrates in which the TCEP-mediated reduction of the disulfide bond and its subsequent addition to the methacrylate group anchored in SBA-15 in one-pot were used to synthesize a silica-protein hybrid material composed of biotin-labeled SBA-15 and streptavidin. Electrochemically active material was synthesized from the reaction of ferrocene-containing thiol and the methacrylate-labeled SBA-15. The ease of synthesis for the methacrylate-labeled SBA-15 material together with its ability to undergo efficient chemoselective thiol-ene reaction would make it a very attractive platform for the development of covalently anchored enzymes and sensors.

}, issn = {1932-7447}, doi = {10.1021/jp2056442}, author = {Kumari, Sushma and Malvi, Bharmana and Ganai, Anal Kumar and Pillai, Vijayamohanan K. and Sen Gupta, Sayam} } @article { ISI:000289692500038, title = {Synthesis and characterization of poly-L-lysine grafted SBA-15 using NCA polymerization and click chemistry}, journal = {Journal of Materials Chemistry}, volume = {21}, number = {18}, year = {2011}, month = {APR}, pages = {6690-6697}, publisher = {ROYAL SOC CHEMISTRY}, type = {Article}, address = {THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND}, abstract = {

Poly-L-lysine (PLL) grafted ordered mesoporous material was prepared by a combination of NCA polymerization and click chemistry. Large pore SBA-15 with a mesopore diameter of similar to 12 nm was synthesized using a previously reported method. The surface of this SBA-15 material was modified with azidopropyl groups. This {\textquoteleft}{\textquoteleft}clickable{\textquoteright}{\textquoteright} SBA-15 was then reacted with an alkyne terminated poly-L-lysine synthesized by the ring-opening polymerization of 3-cbz-L-lysine NCA with N-TMS propargylamine as the initiator. This procedure allows grafting of a uniform polymer film with a high polymer loading. No appreciable pore blocking was observed upon grafting of PLL. No change in the periodic structure of the SBA-15 was observed throughout the grafting process. The SBA-15 PLL conjugate was characterized using (13)C and (29)Si NMR, XRD, FT-IR, N(2) adsorption-desorption and thermogravimetry. The results indicate that polypeptides can be easily grafted onto various ordered mesoporous materials by this {\textquoteleft}{\textquoteleft}grafting to{\textquoteright}{\textquoteright} methodology with accessible pores and high loadings of the polypeptide.

}, issn = {0959-9428}, doi = {10.1039/c0jm04589f}, author = {Kar, Mrityunjoy and Malvi, Bharmana and Das, Anindita and Panneri, Suyana and Sen Gupta, Sayam} } @article { ISI:000306280700023, title = {Encapsulation of enzyme in large mesoporous material with small mesoporous windows}, journal = {Chemical Communications}, volume = {48}, number = {63}, year = {2012}, month = {JUN}, pages = {7853-7855}, publisher = {ROYAL SOC CHEMISTRY}, type = {Article}, address = {THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND}, abstract = {

Trypsin has been encapsulated in the mesopores of a hierarchical mesoporous silica material synthesized via Cu(I) catalyzed azide-alkyne click reaction between azide functionalized large spherical SBA-15 particles and alkyne functionalized mesoporous silica nanoparticles (MSNs). Encapsulated trypsin functions as an efficient biocatalyst and can be recycled several times.

}, issn = {1359-7345}, doi = {10.1039/c2cc33592a}, author = {Malvi, Bharmana and Sen Gupta, Sayam} } @article { ISI:000303442500016, title = {One pot glucose detection by [Fe-III(biuret-amide)] immobilized on mesoporous silica nanoparticles: an efficient HRP mimic}, journal = {Chemical Communications}, volume = {48}, number = {43}, year = {2012}, month = {APR}, pages = {5289-5291}, publisher = {ROYAL SOC CHEMISTRY}, type = {Article}, address = {THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND}, abstract = {

An [Fe-III(biuret-amide)] complex has been immobilized onto mesoporous silica nanoparticles via Cu(I) catalyzed azide-alkyne click chemistry. This hybrid material functions as an efficient peroxidase mimic and was successfully used for the quantitative determination of hydrogen peroxide and glucose via a one-pot colorimetric assay.

}, issn = {1359-7345}, doi = {10.1039/c2cc30970j}, author = {Malvi, Bharmana and Panda, Chakadola and Dhar, Basab B. and Sen Gupta, Sayam} } @article { ISI:000315168800013, title = {Catalytic signal amplification using [Fe-III(biuret-amide)]-mesoporous silica nanoparticles: visual cyanide detection}, journal = {Chemical Communications}, volume = {49}, number = {22}, year = {2013}, month = {MAR}, pages = {2216-2218}, publisher = {ROYAL SOC CHEMISTRY}, type = {Article}, address = {THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND}, abstract = {

Catalytic signal amplification was used for the colorimetric detection of CN- in aqueous media by using the enzyme catalase in tandem with mesoporous silica nanoparticle based synthetic HRP enzyme mimic Fe-MSNs. Signal amplification up to a maximum of eight fold was observed for the reporter {\textquoteleft}{\textquoteleft}oxidized TMB{\textquoteright}{\textquoteright} with respect to the added CN- ion.

}, issn = {1359-7345}, doi = {10.1039/c3cc38932d}, author = {Panda, Chakadola and Dhar, Basab B. and Malvi, Bharmana and Bhattacharjee, Yudhajit and Sen Gupta, Sayam} } @article { ISI:000332835300494, title = {Homogeneous water oxidation using peroxidase mimic [Fe-III(biuret-amide)] and analyte detection via signal amplification}, journal = {Journal of Biological Inorganic Chemistry}, volume = {19}, number = {1}, year = {2014}, note = {16th International Conference on Biological Inorganic Chemistry (ICBIC), Grenoble, FRANCE, JUL 22-26, 2013}, month = {MAR}, pages = {S557}, publisher = {Int Organizing Comm; Natl Organizing Comm; SBIC; Veolia Environm; Arcane; Grenoble Innovat Adv New Technologies; LOREAL; Soc Chimique France; CEA, Life Sci Div; SHIMADZU; High Tech Mat; CEA, Div Matter Sci; IFP Energies Nouvelles; Univ Joseph Fourier; Spr}, address = {233 SPRING ST, NEW YORK, NY 10013 USA}, issn = {0949-8257}, author = {Panda, C. and Dhar, B. B. and Ghosh, Munmun and Malvi, Bharmana and Bhattacharjee, Yudhajit and Sengupta, S.} }