@article { ISI:000325642400017,
	title = {Electrophile induced branching cascade: a powerful approach to access various molecular scaffolds and their exploration as novel anti-mycobacterial agents},
	journal = {Chemical Communications},
	volume = {49},
	number = {86},
	year = {2013},
	month = {SEP},
	pages = {10109-10111},
	publisher = {ROYAL SOC CHEMISTRY},
	address = {THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND},
	abstract = {<p>Herein we report on the Electrophile Induced Branching Cascade (EIBC), a new technique to produce a variety of biologically important molecular scaffolds. Some compounds exhibit excellent activities against Mycobacterium smegmatis.</p>},
	issn = {1359-7345},
	doi = {10.1039/c3cc45289a},
	author = {Patil, Nitin T. and Konala, Ashok and Sravanti, Sudha and Singh, Ashita and Ummanni, Ramesh and Sridhar, Balasubramanian}
}
@article {42900,
	title = {Repurposing of a drug scaffold: identification of novel sila analogues of rimonabant as potent antitubercular agents},
	journal = {European Journal of Medicinal Chemistry},
	volume = {122},
	year = {2016},
	month = {OCT},
	pages = {723-730},
	abstract = {<p>The structural similarity between an MmpL3 inhibitor BM212, and a cannabinoid receptor modulator rimonabant, prompted us to investigate the anti-tubercular activity of rimonabant and its analogues. Further optimization, particularly through incorporation of silicon into the scaffold, resulted in new compounds with significant improvement in anti-tubercular activity against Mycobacterium tuberculosis (H37Rv). The sila analogue 18a was found to be the most potent antimycobacterial compound (MIC, 31 ng/mL) from this series with an excellent selectivity index. (C) 2016 Elsevier Masson SAS. All rights reserved.</p>},
	doi = {10.1016/j.ejmech.2016.07.009},
	author = {Ramesh, Remya and Shingare, Rahul D. and Kumar, Vinod and Anand, Amitesh and Swetha, B. and Veeraraghavan, Sridhar and Viswanadha, Srikant and Ummanni, Ramesh and Gokhale, Rajesh S. and Reddy, D. Srinivasa}
}
