@article {48009,
	title = {cis-aziridine synthon based synthetic investigation for tamiflu employing horner-wadsworth-emmons reaction},
	journal = {European Journal of Organic Chemistry},
	volume = {2022},
	year = {2022},
	month = {JUL },
	pages = {e202200384},
	type = {Article},
	abstract = {<p>
	Synthetic investigations to achieve a novel intermediate of Tamiflu by using cis-aziridine as a chiral building block, which is readily synthesized from (D)-mannitol as a renewable starting material, has been presented. The present approach utilizes the intramolecular Horner-Wadsworth-Emmons reaction as the key step for the synthesis of Tamiflu. On the other hand, diene containing allylic aziridine framework is found to be inefficient to furnish the six-membered core skeleton of Tamiflu through ring-closing metathesis reaction.</p>
},
	keywords = {Aziridine, cyclization, HWE reaction, Metathesis, Tamiflu},
	issn = {1434-193X},
	doi = {10.1002/ejoc.202200384},
	author = {Chavan, Subhash P. and Kawale, Sanket A. and Gonnade, Rajesh G.}
}
@article {48718,
	title = {Rapid bioinspired N-acyliminium ion strategy for the ABC core of the stemona alkaloids},
	journal = {Asian Journal of Organic Chemistry},
	volume = {12},
	year = {2023},
	month = {SEP},
	type = {Article},
	abstract = {<p>
	A concise and highly diastereoselective bioinspired key cationic cyclization strategy for the asymmetric synthesis of the tricyclic core of the (-)-stemoamide, together with 8,9-bis-epi-stemoamide has been described. The key N-acyliminium ion precursors were accessed from L-tartaric acid and L-malic acid respectively. The use of ethyl acetoacetate derived bifunctional allylidenetriphenylphosphorane reagent in the early stage of the synthetic strategy is advantageous for the rapid construction of highly functionalized key pyrrolo[1,2-\&amp; alpha;]azepine frameworks.</p>
},
	keywords = {alkaloids, Biomimetic synthesis, Claisen rearrangement, cyclization, Regioselectivity},
	issn = {2193-5807},
	doi = {10.1002/ajoc.202300331},
	author = {Chavan, Subhash P. and Kalbhor, Dinesh B. and Gonnade, Rajesh G.}
}
