@article { ISI:000318901000001,
	title = {Draft genome of ochrobactrum intermedium strain M86 isolated from non-ulcer dyspeptic individual from India},
	journal = {GUT Pathogens},
	volume = {5},
	year = {2013},
	month = {APR},
	pages = {7},
	publisher = {BIOMED CENTRAL LTD},
	address = {236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8HL, ENGLAND},
	abstract = {<p>Background: Ochrobactrum intermedium is an emerging opportunistic pathogen of humans that is closely related to members of the genus Brucella. Earlier, we reported the case of an Indian subject with non-ulcer dyspeptic symptoms whose urease positive gastric biopsy revealed the presence of Helicobacter pylori along with non-Helicobacter like bacteria, eventually cultured and identified as O. intermedium strain M86. Results: Here, we describe the unclosed draft genome of the strain M86 with a length of 5,188,688 bp and mean G+C content of 57.9\%. We have also identified many putative gene clusters that might be responsible for its persistence in the gastric mucosa. Comparative analysis of genomic features of Ochrobactrum intermedium strain M86 and Ochrobactrum intermedium LMG 3301(T) was also done. Conclusions: This paper attempts to gain whole-genome based insights into the putative gene determinants of O. intermedium for survival in the highly acidic stomach lumen environment. Identification of genes putatively involved in the various metabolic pathways may lead to a better understanding of the survival of O. intermdedium in acidic condition.</p>},
	issn = {1757-4749},
	doi = {10.1186/1757-4749-5-7},
	author = {Kulkarni, Girish and Dhotre, Dhiraj and Dharne, Mahesh S. and Shetty, Sudarshan and Chowdhury, Somak and Misra, Vatsala and Misra, Sriprakash and Patole, Milind and Shouche, Yogesh}
}
@article {43941,
	title = {Multilocus sequence typing of Ochrobactrum spp. isolated from gastric niche},
	journal = {Journal of Infection and Public Health },
	volume = {10},
	year = {2017},
	month = {MAR-APR},
	pages = {201-210},
	type = {Journal Article},
	abstract = {The human stomach is colonized by diverse bacterial species. The presence of non-Helicobacter pylori bacteria in urease-positive biopsies of individuals has been reported. Bacteria belonging to the Ochrobactrum genus have been documented in the human gastric niche. The co-occurrence of Ochrobactrum spp. with H. pylori was previously reported in an antral biopsy of a non-ulcer dyspeptic (NUD) subject from Northern India. There is no information on the genetic diversity of Ochrobactrum spp. isolated from the gastric niche in the stomach. We aimed to study the species distribution and diversity of Ochrobactrum spp. with and without H. pylori in urease-positive biopsies across three different geographical regions in India. Sixty-two Ochrobactrum isolates recovered from patients with an upper gastric disorder (n=218) were subjected to molecular identification and multilocus sequence typing. H. pylori DNA was found in the majority of biopsies, which had a variable degree of Ochrobactrum spp present. Interestingly, some of the urease-positive biopsies only had Ochrobactrum without any H. pylori DNA. Based on phylogenetic analysis, the Ochrobactrum isolates were distributed into the O. intermedium, O. anthropi and O. oryzae groups. This indicates there are multiple species in the gastric niche irrespective of the presence or absence of H. pylori. Antibiotyping based on colistin and polymyxin B could differentiate between O. intermedium and O. anthropi without revealing the resistance-driven diversity. Considering the prevalence of multiple Ochrobactrum spp. in the human gastric niche, it is important to evaluate the commensal and/or pathogenic nature of non-H. pylori bacteria with respect to their geographical distribution, lifestyle and nutrition needs.},
	keywords = {Helicobater Pyroli, MLST, Non-Ulcer Dyspepsia, Ochrobactrum},
	doi = {10.1016/j.jiph.2016.04.013},
	author = {Kulkarni, Girish},
	editor = {Gohil, Kushal}
}
