@article { ISI:000269337500015,
	title = {Highly diastereoselective 1,3-dipolar cycloaddition of a D-galactose-derived nitrone with dimethyl maleate: synthesis of polyhydroxylated perhydroazaazulenes},
	journal = {Synlett},
	number = {12},
	year = {2009},
	month = {JUL},
	pages = {1959-1963},
	publisher = {GEORG THIEME VERLAG KG},
	address = {RUDIGERSTR 14, D-70469 STUTTGART, GERMANY},
	abstract = {<p>An intermolecular 1,3-dipolar cycloaddition of a D-galactose-derived nitrone with dimethyl maleate was found to be perfectly diastereoselective at the nitrone carbon to give exclusive formation of isoxazolidine. The N-O bond reductive cleavage in isoxazolidine followed by lactam reduction afforded a pyrrolidine ring skeleton with sugar appendage that on acetonide cleavage and reductive amino-cyclization gave hitherto unknown hydroxymethyl-substituted hexa- and pentahydroxy perhydroazaazulenes.</p>},
	keywords = {1, 3-dipolar nitrone olefin cycloaddition (DNOC), diastereoselectivity, Iminosugars, inhibitors, nitrone},
	issn = {0936-5214},
	doi = {10.1055/s-0029-1217541},
	author = {Bande, Omprakash P. and Jadhav, Vrushali H. and Puranik, Vedavati G. and Dhavale, Dilip D.}
}
