@article {48121,
	title = {Crystalline xylitol production from corncob biomass with oral toxicity analysis},
	journal = {Industrial Crops and Products},
	volume = {187},
	year = {2022},
	month = {NOV },
	pages = {115407},
	type = {Article},
	abstract = {<p>
	Xylitol, a five-carbon sugar alcohol, has a steady global market and finds application as a natural sugar substitute in various food and confectionery products. Biocatalytic xylitol production, although touted as a greener alternative to conventional chemical catalysis, suffers from certain challenges, the primary being high cost of production. This study demonstrates a process for food-grade xylitol production from corncob biomass with energy reduction through two major process modifications. A non-conventional fermentation strategy was adopted whereby adjusting aeration without agitation, xylitol with high yield (0.86 +/- 0.015 g/g), and productivity (0.74 gL(-1)h(-1)) could be produced by a GRAS Pichia caribbica MTCC 5703 strain. Xylitol was recovered from the broth in the form of crystals using a combination of membrane-based filtration and crystallization. The crystals demonstrated similar to 98 \% purity when quantified with H-1 NMR. Oral toxicity analysis of the crystals demonstrated no adverse effect in female Winstar rats (at a loading of 2000 mg/kg body weight of animals). Overall process statistics showed that 0.584 kg of food-grade xylitol crystals could be produced from 3.5 kg of corncob biomass. The two-process modifications during fermentation and xylitol recovery enabled an energy saving of similar to 20.842 kW/kg of crystals, providing tremendous advantages for biorefinery-based large-scale xylitol production from corncob biomass.</p>
},
	keywords = {Biomass, Fermentation, Oral toxicity analysis, Wastewater treatment, xylitol},
	issn = {0926-6690},
	doi = {10.1016/j.indcrop.2022.115407},
	author = {Ahuja, Vishal and Dasgupta, Diptarka and Kshirsagar, Siddheshwar and Ghosh, Prasenjit and More, Snehal and Gupta, Piyush and Behera, Babita and Bhaskar, Thallada}
}
@article {49141,
	title = {Challenges and opportunities for production of C5 sugar fatty acid esters (SFAEs) from renewable resources},
	journal = {Industrial Crops and Products},
	volume = {193},
	year = {2023},
	month = {MAR},
	pages = {116170},
	type = {Article},
	abstract = {<p>
	Sugar fatty acid esters represent a billion-dollar market with huge global demand. Although glucose and sucrose-based surfactants have prevailed in the chemical industry for decades, C-5-based esters are relatively unknown and have recently started to gain attention owing to their multifunctional properties. These molecules can be derived from cheap and inexpensive biomass/renewable resources and present promising potential with diverse applications as additives in various nutraceutical, pharmaceutical, and cosmeceutical formulations. However, large-scale production of C-5 sugar esters is limited, with one or two commercial plants operating worldwide. This review highlights the major challenges and prospects of biotechnological production of the C-5 sugar esters, considering the possible advancements over existing technology with various aspects of industrial bioprocessing and product recovery.</p>
},
	keywords = {Bioprocess, C-5-fatty acid esters, Lipase, solvent, xylitol},
	issn = {0926-6690},
	doi = {10.1016/j.indcrop.2022.116170},
	author = {Tracy, Preetanshika and Dasgupta, Diptarka and More, Snehal}
}
