@article { ISI:000339012400004,
	title = {Biocatalyst mediated functionalization of salannin, an insecticidal limonoid},
	journal = {RSC Advances},
	volume = {4},
	number = {53},
	year = {2014},
	month = {JUN},
	pages = {27661-27664},
	publisher = {ROYAL SOC CHEMISTRY},
	type = {Article},
	address = {THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND},
	abstract = {<p>Transformation of salannin, an insecticidal C-seco limonoid was investigated using a fungal system, Cunninghamella echinulata. Salannin was efficiently converted into two metabolites, where the C-17 furan moiety was transformed into gamma-hydroxybutenolide (salanninolide) and N-(2-hydroxyethyl)-alpha,beta-unsaturated-gamma-lactam (salanninactam) analogues. Present studies have indicated salanninolide to be a metabolite in the C-seco limonoid biosynthetic pathway.</p>},
	issn = {2046-2069},
	doi = {10.1039/c4ra04652h},
	author = {Haldar, Saikat and Kolet, Swati P. and Dandekar, Devdutta S. and Kale, Balaji S. and Gonnade, Rajesh G. and Thulasiram, Hirekodathakallu V.}
}
@article { ISI:000336115000029,
	title = {Lipase mediated separation of triterpene structural isomers, alpha- and beta-amyrin},
	journal = {Tetrahedron Letters},
	volume = {55},
	number = {19},
	year = {2014},
	month = {MAY},
	pages = {3122-3125},
	publisher = {PERGAMON-ELSEVIER SCIENCE LTD},
	address = {THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND},
	abstract = {<p>Pentacyclic triterpenoids alpha- and beta-amyrin possess a wide range of biological and pharmacological activities. High structural similarity between these two structural isomers makes their chromatographic separation an ineffective and tedious choice. In this study, Candida rugosa lipase catalyzed separation protocol for the isolation of individual isomers has been developed. In the presence of vinyl acetate as the acyl donor, Candida rugosa lipase carried out acetylation of beta-amyrin more efficiently as compared to alpha-amyrin leading to a kinetic separation. The conditions of transesterification reaction were optimized systematically, which was utilized to separate alpha- and beta-amyrin from a mixture obtained from the latex of Plumeria obtusa. (C) 2014 Elsevier Ltd. All rights reserved.</p>},
	keywords = {Amyrin, Candida rugosa, Kinetic separation, Lipase, Structural isomer},
	issn = {0040-4039},
	doi = {10.1016/j.tetlet.2014.04.015},
	author = {Haldar, Saikat and Kale, Balaji S. and Jadhav, Dipesh D. and Thulasiram, Hirekodathakallu V.}
}
