@article { ISI:000240186500039, title = {Cyanuric chloride: Trichloro-1,3,5-triazine}, journal = {Synlett}, number = {13}, year = {2006}, month = {AUG}, pages = {2156-2157}, publisher = {GEORG THIEME VERLAG KG}, type = {Article}, address = {RUDIGERSTR 14, D-70469 STUTTGART, GERMANY}, issn = {0936-5214}, doi = {10.1055/s-2006-948185}, author = {Haval, Kishan P.} } @article { ISI:000236437400010, title = {Haval-Argade contrathermodynamic rearrangement of alkylidenesuccinimides to alkylmaleimides via the corresponding isoimides: a general approach to alkyl and dialkyl substituted maleimides}, journal = {Tetrahedron}, volume = {62}, number = {15}, year = {2006}, month = {APR}, pages = {3557-3563}, publisher = {PERGAMON-ELSEVIER SCIENCE LTD}, type = {Article}, address = {THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND}, abstract = {

A simple and efficient access to alkyl and dialkyl substituted maleimides has been demonstrated via the new contrathermodynamic rearrangement of (E)-alkylidenesuccinimides to alkylinaleimides. The (E)-alkylidenesuccinimides obtained from the Wittig-condensation of N-arylmaleimide with aliphatic aldehydes oil regioselective hydrolysis furnished the corresponding (E)-alkylidenesuccinanilic acids in 95-98\% yields. The beta-alkylidenesuccinanilic acids oil treatment with cyanuric chloride in the presence of triethylamine gave the corresponding beta-alkylisomaleimides in 78-80\% yields via the beta-alkylideneisosuccinimides with the exocyclic to endocyclic carbon-carbon double bond migration. The kinetically controlled products alkylisomaleimides in refluxing acetic acid furnished the thermodynamically controlled alkylinaleimides in 98\% yield. The Wittig condensation of alkyl substituted isomaleimides/maleimides with aliphatic aldehydes gave the desired dialkyl substituted maleimides in high yields. A conversion of alpha-methylenesuccinanilic acids to alpha-methylisomaleimides has also been described, with 90\% yield. (c) 2006 Elsevier Ltd. All rights reserved.

}, keywords = {alkyl and dialkylmaleimides, contrathermodynamic rearrangement, isomaleimides, maleimides, wittig coupling}, issn = {0040-4020}, doi = {10.1016/j.tet.2006.01.091}, author = {Haval, Kishan P. and N. P. Argade} } @article {42600, title = {Synthesis of natural fimbrolides}, journal = {Synthesis-Stuttgart}, year = {2007}, month = {JUL}, pages = {2198-2202}, doi = {10.1055/s-2007-983755}, author = {Haval, Kishan P. and N. P. Argade} } @article { ISI:000258908000075, title = {General strategy for the synthesis of natural and unnatural dialkylmaleic anhydrides}, journal = {Journal of Organic Chemistry}, volume = {73}, number = {17}, year = {2008}, month = {SEP}, pages = {6936-6938}, publisher = {AMER CHEMICAL SOC}, type = {Article}, address = {1155 16TH ST, NW, WASHINGTON, DC 20036 USA}, abstract = {

Starting from alkylidenesuccinimides, a wide range of dialkylmaleic anhydrides have been synthesized via the generation of a carbanion on a succinimide unit and its condensation with various alkyl halides as the key reaction.

}, issn = {0022-3263}, doi = {10.1021/jo801284r}, author = {Haval, Kishan P. and N. P. Argade} } @article { ISI:000342927000001, title = {Concise account of the chemistry of valuable alkyl(methyl)maleic anhydrides}, journal = {Synthesis-Stuttgart}, volume = {46}, number = {20}, year = {2014}, month = {OCT}, pages = {2683-2700}, publisher = {GEORG THIEME VERLAG KG}, type = {Review}, address = {RUDIGERSTR 14, D-70469 STUTTGART, GERMANY}, abstract = {

A large number of significant bioactive natural and synthetic alkyl(methyl)maleic anhydrides are known in the contemporary literature. A broad range of suitably functionalized substrates have been tailored to accomplish concise and efficient syntheses of an array of alkyl(methyl)maleic anhydrides employing a variety of elegant synthetic strategies. This review presents a brief literature account of the isolation and activity of these important target compounds with a special emphasis on their synthesis.

}, keywords = {alkyl(methyl)maleic anhydrides, bioactivity, dimethylmaleic anhydride, isolation, nucleophilic reactions, Total synthesis}, issn = {0039-7881}, doi = {10.1055/s-0034-1378665}, author = {Deore, Prashant S. and Haval, Kishan P. and Gadre, Smita R. and N. P. Argade} }