@article {49539,
	title = {Aryl borane as a catalyst for dehydrative amide synthesis},
	journal = {Journal of Organic Chemistry},
	volume = {90},
	year = {2025},
	month = {JAN},
	pages = {2271-2277},
	type = {Article},
	abstract = {<p>
	Tris(pentafluorophenyl)borane B(C6F5)(3)H2O is reported as a catalyst for dehydrative amidation of carboxylic acids and amines. This protocol is applicable across a wide range of \&gt;35 substrates, including aromatic and aliphatic amines and acids, resulting in amides in \&lt;= 92\% yields. The scalability of the reaction up to 10 mmol, along with the synthesis of drugs such as ibuprofen amide, moclobemide, and phenacetin, demonstrates the industrial potential of our protocol.</p>
},
	issn = {0022-3263},
	doi = {10.1021/acs.joc.4c02652},
	author = {Gavit, Amit Vinayak and Talekar, Sanjana S. and Mane, Manoj V. and Sawant, Dinesh Nanaji}
}
