@article { ISI:000294656400011,
	title = {One-step stereospecific strategy for the construction of the core structure of the 5,11-methanomorphanthridine alkaloids in racemic as well as in optically pure form: synthesis of (+/-)-pancracine and (+/-)-brunsvigine},
	journal = {European Journal of Organic Chemistry},
	number = {24},
	year = {2011},
	month = {AUG},
	pages = {4571-4587},
	publisher = {WILEY-V C H VERLAG GMBH},
	address = {PO BOX 10 11 61, D-69451 WEINHEIM, GERMANY},
	abstract = {<p>The unique core structure of the complex pentacyclic 5,11-methanomorphanthridine has been constructed stereospecifically in one step by an intramolecular [3+2] cycloaddition of a non-stabilized azomethine ylide (AMY), generated by the sequential double desilylation of 14 using (AgF)-F-I as a one-electron oxidant. The formation of the single diastereomer in the key step is explained by the preferred transition state produced by endo attack of the AMY on the {\textquoteleft}{\textquoteleft}Re{\textquoteright}{\textquoteright} face of the dipolarophile. An asymmetric version of the cycloaddition using a chiral dipolarophile was applied to construct the core structure 68 with 63 \% ee. This strategy was successfully applied to the formal synthesis of (+/-)-pancracine and the total synthesis of (+/-)-brunsvigine. An unprecedented and interesting skeletal rearrangement product 49 was observed during the attempted assembly of the E ring from 46 through Horner-Wadsworth-Emmons reactions. Mechanisms involving azetidinium salt formation or the Grob-type fragmentation are advanced to explain the observed rearrangement.</p>},
	keywords = {alkaloids, Azomethine ylides, Cycloaddition, Ring-closing metathesis, synthesis design},
	issn = {1434-193X},
	doi = {10.1002/ejoc.201100601},
	author = {Pandey, Ganesh and Kumar, Ravindra and Banerjee, Prabal and Puranik, Vedavati G.}
}
@article { ISI:000310215100010,
	title = {Organocatalytic dynamic kinetic resolution via conjugate addition: synthesis of chiral trans-2,5-dialkylcyclohexanones},
	journal = {Organic \& Biomolecular Chemistry},
	volume = {10},
	number = {41},
	year = {2012},
	month = {AUG},
	pages = {8260-8267},
	publisher = {ROYAL SOC CHEMISTRY},
	type = {Article},
	address = {THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND},
	abstract = {<p>A novel strategy of initiating an organocatalysed dynamic kinetic resolution (dr up to 99 : 1 and er up to 94 : 6) for the synthesis of chiral trans-2,5-dialkylcyclohexanones by an asymmetric conjugate addition of dimethyl malonate on to 6-substituted cyclohexenones is reported.</p>},
	issn = {1477-0520},
	doi = {10.1039/c2ob26597d},
	author = {Pandey, Ganesh and Adate, Priyanka A. and Puranik, Vedavati G.}
}
