@article {49205,
	title = {Catalytic cycloisomerization-oxidative cyclization reaction sequence of enyne diesters derived from 2-propargyloxyarylaldehydes},
	journal = {Organic Letters},
	volume = {26},
	year = {2024},
	month = {NOV },
	pages = {9793-9798},
	type = {Article},
	abstract = {<p>
	Enyne diesters derived from 2-propargyloxyarylaldehydes are converted into 2-oxopyranochromenes via In(OTf)3-catalyzed cycloisomerization and 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ)-mediated oxidative cyclization reaction sequence in one pot. The process possesses broad substrate scope and good functional group compatibility and generates various 4-(hetero)aryl-substituted 2-oxopyranochromenes in 32-79\% yields (over two steps). 2-Oxopyranochromenes undergo selective decarboxylation under Krapcho conditions. When treated with aliphatic secondary amines in DMF, 2-oxopyranochromenes undergo decarboxylative amination at ambient temperature to generate 2-amino-substituted functionalized chromenes in good yields.</p>
},
	issn = {1523-7060},
	doi = {10.1021/acs.orglett.4c03856},
	author = {Prajapati, Karmdeo and Saini, Manoj Kumar and Gonnade, Rajesh G. and Basak, Ashok K.}
}
