@article {49086, title = {Diastereoselective synthesis of functionalized spiroindolines via intramolecular ipso-iodocyclization/nucleophile addition cascade reactions of indole-tethered ynones}, journal = {Organic and biomolecular chemistry}, volume = {22}, year = {2024}, month = {MAY }, pages = {3415-3419}, type = {Article}, abstract = {

Herein, we describe a highly diastereoselective approach for synthesizing polyfunctionalized spiroindolines from indolyl-ynones involving an ipso-iodocyclization/nucleophile addition cascade. The developed strategy allows the formation of a spirocyclic core and the installation of two functional groups in a single operation. Also this strategy is accompanied by the generation of two C-C and one C-I bonds and two contiguous stereocenters.

}, issn = {1477-0520}, doi = {10.1039/d4ob00112e}, author = {Bag, Debojyoti and Sawant, Sanghapal D.} } @article {49228, title = {Divergent synthesis of unsymmetrical Bis-heteroaryl ketones via base-promoted cascade reactions of 1,2-alkynedione-derived N-propargylic β-enaminones}, journal = {JOURNAL OF ORGANIC CHEMISTRY}, volume = {89}, year = {2024}, month = {AUG }, pages = {11665-11670}, type = {Journal Article}, keywords = {ASYMMETRIC-SYNTHESIS, heterocycles, intramolecular cyclization, pyrroles}, issn = {0022-3263}, doi = {10.1021/acs.joc.4c01407}, author = {Bag, Debojyoti and Saini, Sheetal and Rathod, Mahesh S. and Sawant, Sanghapal D.} } @article {49353, title = {Modular synthesis of unsymmetrical indolyl diketones from ynediones via sequential aza-Michael addition/C-H functionalization}, journal = {Organic \& Biomolecular Chemistry}, volume = {22}, year = {2024}, month = {OCT }, pages = {8152-8156}, type = {Article}, abstract = {

Herein, we disclose an efficient approach for the synthesis of unsymmetrical indolyl diketones from easily accessible 1,2-alkynediones involving a sequential aza-Michael addition/C-H Functionalization process. The two-step, one-pot strategy involves the aza-Michael addition of an aniline generating the N-aryl enaminones followed by iodine-mediated C-H functionalization.

}, issn = {1477-0520}, doi = {10.1039/d4ob00946k}, author = {Naveed, Abdul and Bag, Debojyoti and Sawant, Sanghapal D.} } @article {49546, title = {Interrupted borrowing hydrogen strategy enabled aminomethylation and direct cross-dehydrogenative coupling strategy enabled dicarbonylation reactions of imidazo[1,5-a]pyridines}, journal = {Chemical Communications}, volume = {61}, year = {2025}, month = {FEB}, pages = {3021-3024}, type = {Article}, abstract = {

Herein, we disclose the development of novel aminomethylation and dicarbonylation reactions of imidazo[1,5-a]pyridines. The developed aminomethylation strategy involves a Pd-catalyzed interrupted borrowing hydrogen strategy by utilizing MeOH as the methylene source. A wide variety of imidazo[1,5-a]pyridines and secondary amines were explored for the developed strategy. The established imidazo[1,5-a]pyridine dicarbonylation strategy involves a catalyst/additive-free direct cross-dehydrogenative coupling reaction between imidazo[1,5-a]pyridines and 2-oxoaldehydes.

}, issn = {1359-7345}, doi = {10.1039/d4cc06272h}, author = {Mahajan, Shivangani and Bag, Debojyoti and Kour, Harpreet and Sawant, Sanghapal D.} } @article {49547, title = {Synthesis of isatins via oxone{\textregistered} /TBAI-mediated on-water oxidation of indoles}, journal = {Synthesis-Stuttgart}, volume = {57}, year = {2025}, month = {MAY}, pages = {1583-1591}, type = {Article}, abstract = {

Isatins and their derivatives are important scaffolds in a wide range of pharmaceuticals, bioactive compounds, and functional materials. Herein we describe a new strategy for the synthesis of isatins from indoles via Oxone (R)/TBAI-mediated oxidative dearomatization of indoles in water. The strategy works well with a variety of N-protected indoles and azaindoles.

}, keywords = {dearomatization, indoles, isatins, Oxidation, Water}, issn = {0039-7881}, doi = {10.1055/a-2492-3240}, author = {Khajuria, Pratiksha and Bag, Debojyoti and Sawant, Sanghapal D.} }