@article {49359,
	title = {C-H functionalization of imidazo[1,5-a]pyridines: a metal-free approach for methylene insertion to access C(sp2)-C(sp3)-H-C(sp2) bond formation},
	journal = {ACS Omega},
	volume = {9},
	year = {2024},
	month = {DEC },
	pages = {49071-49080},
	type = {Article},
	abstract = {<p>
	Formaldehyde has been used as a solvent and a source of carbon to insert a methylene group for bridging two imidazo[1,5-a]pyridine molecules without using any metal catalysis. This strategy has been extended on other alkyl-, aryl-, and heteroaryl aldehydes as well. This C(sp2)-C(sp3)-H-C(sp2) bond forming reaction proceeds via C(sp2)H functionalization of imidazo[1,5-a]pyridine and was applied on a wide range of substrates offering moderate to good yields of methylene-bridged/inserted bis-imidazo[1,5-a]pyridines. Most importantly, as an application, the bis-heteroarene product has been demonstrated as a ligand. The ligand-like behavior of bis-imidazo[1,5-a]pyridines has been demonstrated as an extension of current methodology. This reaction works well at the gram scale level.</p>
},
	issn = {2470-1343},
	doi = {10.1021/acsomega.4c03823},
	author = {Mahajan, Shivangani and Sawant, Sanghapal D.}
}
@article {50073,
	title = {Cu(ii)/I2 mediated synthesis of α-keto esters via C(sp2)-C(sp) bond cleavage of 1,2-alkynediones followed by C-O bond formation},
	journal = {New Journal of Chemistry},
	volume = {50},
	year = {2026},
	month = {MAR },
	pages = {5076-5080},
	type = {Article},
	abstract = {<p>
	Herein, we disclose an efficient method for the synthesis of alpha-keto esters through a copper(ii)/iodine-mediated reaction. The transformation involves the selective cleavage of the C(sp2)-C(sp) bond of 1,2-alkynediones, which is subsequently followed by C-O bond formation with alcohols. This protocol offers a broad substrate scope, accommodating a wide range of substrates to furnish the desired alpha-keto esters in good yields.</p>
},
	issn = {1144-0546},
	doi = {10.1039/d6nj00240d},
	author = {Naveed, Abdul and Sawant, Sanghapal D.}
}
