@article {48922,
	title = {Carbamate-Protected (BOC and O-NB) 2-Aminopyrimidinedione-based janus G-C nucleobase motifs as building blocks for supramolecular assembly and smart polymers},
	journal = {Journal of organic chemistry },
	volume = {88},
	year = {2023},
	month = {OCT },
	pages = {14953-14959},
	type = {Article},
	abstract = {<p>In this paper, we report {\textquoteleft}{\textquoteleft}carbamate protected{\textquoteright}{\textquoteright} 2-aminopyrimidinedione-based Janus G-C nucleobases (2-APD Janus G-C nucleobases) featuring polymerizable groups and self-complementary triple H-bonding motifs DDA and AAD as building blocks for developing smart polymers and self-healing materials. The carbamate-masked H-bonding motif, cleavable under acidic (BOC group) or photocleavable (O-nitrobenzyl group) conditions, would facilitate the synthesis of smart polymers by alleviating aggregation during polymerization which in turn would exclude self-assembly-assisted solubility issues. Ready accessibility in excellent yields coupled with the possibility for facile introduction of polymerizable groups would make these building blocks excellent candidates for diverse polymerization applications.</p>
},
	issn = {0022-3263},
	doi = {10.1021/acs.joc.3c01318},
	author = {Singh, Dharmendra and Lakshmi, Durga and Meena, Chhuttan L. and Krishna, Gamidi Rama and Sanjayan, Gangadhar J.}
}
@article {50079,
	title = {Dynamic janus hydrogen bond mimicry unlocks tough, flexible supramolecular elastomers for strain sensing},
	journal = {Chemistry of Materials},
	volume = {38},
	year = {2026},
	month = {MAR},
	pages = {2699-2711},
	type = {Article},
	abstract = {<p>
	Flexible and wearable electronics demand stretchable sensors with polymer elastomers as key matrixes for mechanical flexibility and durability. However, despite their excellent elasticity, their limited mechanical strength remains a challenge. To address this limitation, in this study, we report the rational design of supramolecular polyurethane elastomers (SPUs) incorporating nucleobase-inspired aminopyrimidinedione with DDA-AAD (G-C mimic) reversible triple hydrogen bonds. This dual-domain architecture gives rise to a durable supramolecular network with enhanced mechanical properties, yielding elastomers that are soft, stretchable, and tough. By tuning of the density of dynamic cross-links, mechanical properties were systematically modulated. SPU-0.5 exhibited a maximum tensile strength of 16.14 MPa, representing a 67-fold strength enhancement over that of SPU-0. Although increasing the aminopyrimidinedione (APD) content reduced elongation, SPU-0.2 retained a high elongation of 1060\% and showed the lowest residual strain during cyclic tests. To be of great interest, the activation energy increased with increasing hydrogen bonding content up to SPU-0.1, whereas beyond SPU-0.2 it decreased, likely due to extensive hydrogen bond formation. Furthermore, SPU-0.2-SP, a conductive variant, demonstrated a promising strain-sensing performance even after hundreds of cycles. Overall, the insights gained from this study advance the development of intelligent soft materials and lay the groundwork for next-generation flexible and wearable electronic devices.</p>
},
	issn = {0897-4756},
	doi = {10.1021/acs.chemmater.5c02829},
	author = {Lakshmi, Durga and Wagh, Mahendra A. and Sharma, Aakash and Alam, Md Shafi and Selvan, T. Muthamil and Torris, Arun and Mondal, Titash and Sanjayan, Gangadhar J. and Nair, Kiran Sukumaran}
}
