@article {48757,
	title = {Direct deoxygenation of α-hydroxy and α,β-dihydroxy ketones using a silyl lithium reagent},
	journal = {Journal of Organic Chemistry},
	volume = {88},
	year = {2023},
	month = {SEP},
	pages = {14227-14235},
	type = {Article},
	abstract = {<p>
	A reliable method for the one-step direct deoxygenation of alpha-hydroxy ketones has been developed using a silyl lithium reagent and acetic anhydride. The method is metal-catalyst-free and does not require prefunctionalization of the hydroxy group prior to its removal. Deoxygenation of different primary, secondary, and tertiary alcohols was carried out with up to 98\% isolated yield. Additionally, double deoxygenation was achieved when the present method was applied to alpha,beta-dihydroxy ketones to access the corresponding enones in a single step.</p>
},
	issn = {0022-3263},
	doi = {10.1021/acs.joc.3c01613},
	author = {Zade, Vishal M. and Gangnale, Laxmikant D. and Athawale, Paresh R. and Reddy, D. Srinivasa}
}
