@article { ISI:000373408800021,
	title = {Concise enantioselective synthesis of (+)-sertraline and (-)-CP-52002 using proline catalysis},
	journal = {Tetrahedron Letters},
	volume = {57},
	number = {9},
	year = {2016},
	month = {MAR},
	pages = {1053-1055},
	publisher = {PERGAMON-ELSEVIER SCIENCE LTD},
	address = {THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND},
	abstract = {<p>A short enantioselective synthesis of (+)-sertraline and its C-4 epimer (-)-CP-52002 with an overall yield of 30\%, respectively, as its hydrochloride has been described. The key steps are the proline catalyzed Mannich reaction of acetaldehyde and acid catalyzed intramolecular Friedel-Crafts{\textquoteright} alkylation reaction of olefin proceeding with high optical purities. (C) 2016 Elsevier Ltd. All rights reserved.</p>},
	keywords = {Indatraline, Mannich reaction, Proline catalysis, Sertraline, Tametraline},
	issn = {0040-4039},
	doi = {10.1016/j.tetlet.2016.01.085},
	author = {Kalshetti, Rupali G. and Venkataramasubramanian, V. and Kamble, Sanjay P. and Sudalai, Arumugam}
}
@article {46941,
	title = {Concise enantioselective synthesis of (R)-(+)-goniothalamin oxide, a trypanocidal active agent via L-prolinol catalyzed asymmetric epoxidation of cinnamaldehyde},
	journal = {Indian Journal of Chemistry Section B-Organic Chemistry Including Medicinal Chemistry},
	volume = {59},
	year = {2020},
	month = {MAR},
	pages = {393-398},
	type = {Article},
	abstract = {<p>A short and straight-forward enantioselective synthesis of (R)-(+)-goniothalamin oxide 2 has been achieved with an overall yield of 39\% and 99\% ee. The synthetic approach involves L-prolinol catalyzed asymmetric epoxidation of cinnamaldehyde followed by Lewis acid-mediated diastereoselective allylation of epoxy aldehyde as the key chiral-inducing steps.</p>
},
	keywords = {Allylation, asymmetric epoxidation, Esterification, Grubbs{\textquoteright} catalyst, L-prolinol catalyst, Ring closing metathesis},
	issn = {0376-4699},
	author = {Kumar, B. Senthil and Mandle, Ram D. and Kamble, Sanjay P. and Sudalai, Arumugam}
}
