@article {49652,
	title = {Attempted synthesis of the central 2,2-disubstituted pseudoindoxyl core of Austamide via a [Au]-catalyzed nitroalkyne cycloisomerization and intramolecular [3+2]-cycloaddition},
	journal = {Tetrahedron},
	volume = {167},
	year = {2024},
	month = {NOV },
	pages = {134301},
	type = {Article},
	abstract = {<p>
	Herein, we describe an Au-catalyzed cycloisomerization process of a nitroalkyne that was projected to construct the central 2,2-disubstituted pseudoindoxyl core of the natural product Austamide. Our intended strategy for forging the pseudoindoxyl core is based on the nitroalkyne cycloisomerization followed by a subsequent intramolecular [3 + 2] cycloaddition. However, the [3 + 2] cycloaddition occurred in an undesired manner, ultimately leading to a complex hexacyclic scaffold.</p>
},
	keywords = {Austamide, Gold catalysis, Intramolecular [3+2] cycloaddition, Nitroalkyne cycloisomerization},
	issn = {0040-4020},
	doi = {10.1016/j.tet.2024.134301},
	author = {Halnor, Swapnil V. and Ramana, Chepuri V.}
}
